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I Iijima

Explore the profile of I Iijima including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 84
Followers 0
Related Specialties
Chemistry
Pharmacology
Neurology
Top 10 Co-Authors
M Matsumoto
Y Saiga
Y Matsuoka
T Miyagishima
K C Rice
A Ishida
J Minamikawa
Y Ban
A E JACOBSON
A Brossi
Published In
Chem Pharm Bull (Tokyo)
J Med Chem
J Pharmacobiodyn
Tetrahedron Lett
Science
Affiliations
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Recent Articles
1.
Novel benzoxazole 2,4-thiazolidinediones as potent hypoglycemic agents. Synthesis and structure-activity relationships
Arakawa K, Inamasu M, Matsumoto M, Okumura K, Yasuda K, Akatsuka H, et al.
Chem Pharm Bull (Tokyo) . 1998 Jan; 45(12):1984-93. PMID: 9433768
A new series of benzoxazole 2,4-thiazolidinediones was synthesized and evaluated for hypoglycemic activity in genetically obese and diabetic yellow KK mice. 2-Arylmethyl- and 2-(heteroarylmethyl)benzoxazole derivatives showed far more potent activity...
2.
[A case of intracranial hemorrhage following superior sagittal sinus thrombosis associated with nephrotic syndrome]
Mandai K, Tamaki N, Kurata H, Fukada Y, Iijima I, Nakamura H
No Shinkei Geka . 1998 Jan; 25(12):1101-3. PMID: 9430145
A case of intracranial hemorrhage due to superior sagittal sinus thrombosis occurring in a boy with nephrotic syndrome is described. A twelve-year-old boy with nephrotic syndrome presented sudden onset of...
3.
Effects of methyl (+) (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2- carbodithioate(THC), a new hepatoprotective agent, on protein synthesis and chronic liver injury induced by carbon tetrachroride in rats
Matsumoto M, Matsuoka Y, Saiga Y, Iijima I, Kitamura K, Iwasaki H, et al.
J Pharmacobiodyn . 1987 Dec; 10(12):689-96. PMID: 3451955
The effects of oral administration of methyl (+) (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioa te (THC) on protein synthesis in the liver and chronic liver injury induced by carbon tetrachloride (CCl4) in rats were studied....
4.
Effects of methyl (+)(3S)-1,2,3,4-tetrahydro-3-hydroxy-methyl-beta-carboline-2- carbodithioate (THC), a new hepatoprotective agent, on acute liver injuries induced by various hepatotoxic substances in mice and rats
Matsumoto M, Matsuoka Y, Saiga Y, Iijima I
J Pharmacobiodyn . 1987 Nov; 10(11):599-607. PMID: 3446768
The effects of oral administration of methyl (+)(3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodith ioate (THC) on acute liver injuries induced by carbon tetrachloride (CCl4), bromobenzene (B.B.), D-galactosamine (GALN) and alpha-naphthylisothiocyanate (ANIT) in rats and allyl...
5.
Synthesis of 1,2,3,4-tetrahydro-beta-carboline derivatives as hepatoprotective agents. IV. Positional isomers of 1,2,3,4-tetrahydro-2-methylthiothiocarbonyl-beta-carboline-3- carboxylic acid and its 1-alkylated derivatives
Saiga Y, Iijima I, Ishida A, Miyagishima T, Takamura N, Matsumoto M, et al.
Chem Pharm Bull (Tokyo) . 1987 Sep; 35(9):3705-12. PMID: 3435969
No abstract available.
6.
Synthesis of 1,2,3,4-tetrahydro-beta-carboline derivatives as hepatoprotective agents. III. Introduction of substituents onto methyl 1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate
Saiga Y, Iijima I, Ishida A, Miyagishima T, Homma K, Matsumoto M, et al.
Chem Pharm Bull (Tokyo) . 1987 Aug; 35(8):3284-91. PMID: 3427712
No abstract available.
7.
Synthesis of 1,2,3,4-tetrahydro-beta-carboline derivatives as hepatoprotective agents. II. Alkyl 1,2,3,4-tetrahydro-beta-carboline-2-carbodithioates
Saiga Y, Iijima I, Ishida A, Miyagishima T, Shigezane K, Matsumoto M, et al.
Chem Pharm Bull (Tokyo) . 1987 Aug; 35(8):3262-9. PMID: 3427709
No abstract available.
8.
Synthesis of 1,2,3,4-tetrahydro-beta-carboline derivatives as hepatoprotective agents. I. Dithiocarbamates of several alpha-amino acids
Saiga Y, Iijima I, Ishida A, Miyagishima T, Matsumoto M, Matsuoka Y
Chem Pharm Bull (Tokyo) . 1987 Jul; 35(7):2840-3. PMID: 3677236
No abstract available.
9.
Synthesis and antinociceptive activity of 7-methoxycodeine
Iijima I, Minamikawa J, Rice K, JACOBSON A
J Med Chem . 1978 Dec; 21(12):1320-2. PMID: 722742
(-)-7-Methoxycodeine was synthesized from (-)-1-bromosinomeninone in three steps with an overall yield of 29%. The introduction of the 7-methoxy group into the C ring of codeine did not decrease its...
10.
Studies in the (+)-morphinan series. 5. Synthesis and biological properties of (+)-naloxone
Iijima I, Minamikawa J, JACOBSON A, Brossi A, Rice K
J Med Chem . 1978 Apr; 21(4):398-400. PMID: 206698
(+)-Naloxone was prepared in 26% overall yield in eight steps from (+)-7-bromodihydrocodeinone dimethyl ketal by a synthesis which excluded enantiomeric contamination. (+)-Naloxone was examined in three assay systems and found...