I H Frazer
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Explore the profile of I H Frazer including associated specialties, affiliations and a list of published articles.
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116
Citations
1352
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Recent Articles
1.
Tran M, Yoon S, Teoh M, Andersen S, Lam P, Purdue B, et al.
Front Immunol
. 2022 Aug;
13:911873.
PMID: 35967449
The ability to study cancer-immune cell communication across the whole tumor section without tissue dissociation is needed, especially for cancer immunotherapy development, which requires understanding of molecular mechanisms and discovery...
2.
Chandra J, Woo W, Finlayson N, Liu H, McGrath M, Ladwa R, et al.
Cancer Immunol Immunother
. 2020 Sep;
70(3):743-753.
PMID: 32918586
Background: We conducted a phase 1 dose escalation study (ACTRN12618000140257 registered on 30/01/2018) to evaluate the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) in...
3.
Tuong Z, Noske K, Kuo P, Bashaw A, Teoh S, Frazer I
Papillomavirus Res
. 2018 May;
5:6-20.
PMID: 29807614
Currently available vaccines prevent HPV infection and development of HPV-associated malignancies, but do not cure existing HPV infections and dysplastic lesions. Persistence of infection(s) in immunocompetent patients may reflect induction...
4.
Tran L, Bergot A, Mattarollo S, Mittal D, Frazer I
J Invest Dermatol
. 2014 Apr;
134(9):2438-2446.
PMID: 24732401
We have shown that the expression of human papillomavirus type 16 E7 (HPV16.E7) protein within epithelial cells results in local immune suppression and a weak and ineffective immune response to...
5.
Iliadou A, Evans D, Zhu G, Duffy D, Frazer I, Montgomery G, et al.
J Med Genet
. 2006 Sep;
44(1):24-30.
PMID: 16950815
Background: The red cell indices quantify the size, number and oxygen-carrying ability of erythrocytes. Although the genetic basis of many monogenic forms of anaemia is well understood, comparatively little is...
6.
Tabrizi S, Frazer I, Garland S
Int J Gynecol Cancer
. 2006 Jun;
16(3):1032-5.
PMID: 16803481
This study evaluated the detection of human papillomavirus (HPV) 16 antibody in HPV 16-associated cervical intraepithelial neoplasia (CIN) in Australian women. Seroreactivity to HPV 16 L1 virus-like particles was assessed...
7.
Evans D, Zhu G, Duffy D, Frazer I, Montgomery G, Martin N
Genes Immun
. 2004 Aug;
5(7):548-52.
PMID: 15306848
CD4-CD8 ratio is an important diagnostic measure of immune system functioning. In particular, CD4-CD8 ratio predicts the time taken for progression of HIV infection to acquired immune deficiency syndrome (AIDS)...
8.
Malcolm K, Gill J, Leggatt G, Boyd R, Lambert P, Frazer I
Clin Dev Immunol
. 2004 Feb;
10(2-4):91-103.
PMID: 14768939
Transgenic mice expressing the E7 protein of HPV16 from the keratin 14 promoter demonstrate increasing thymic hypertrophy with age. This hypertrophy is associated with increased absolute numbers of all thymocyte...
9.
Peng S, Zhou J, Frazer I
J Tongji Med Univ
. 2003 Jul;
19(3):170-4, 180.
PMID: 12840887
The green fluorescent protein (GFP) from the jellyfish Aequorea victoria has attracted widespread interest since it was demonstrated to be fluorescent in vivo when expressed in other organisms. In order...
10.
Liu W, Zhao K, Gao F, Leggatt G, Fernando G, Frazer I
Vaccine
. 2001 Dec;
20(5-6):862-9.
PMID: 11738751
Papillomavirus infection is a major antecedent of anogenital malignancy. We have previously established that the L1 and L2 capsid genes of papillomavirus have suboptimal codon usage for expression in mammalian...