I C Le Poole
Overview
Explore the profile of I C Le Poole including associated specialties, affiliations and a list of published articles.
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30
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738
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Recent Articles
1.
Webb K, Tung R, Winterfield L, Gottlieb A, Eby J, Henning S, et al.
Br J Dermatol
. 2015 Jul;
173(3):641-50.
PMID: 26149498
Tumour necrosis factor (TNF)-α, a proinflammatory cytokine central to many autoimmune diseases, has been implicated in the depigmentation process in vitiligo. We review its role in vitiligo by exploring its...
2.
Ezzedine K, Lim H, Suzuki T, Katayama I, Hamzavi I, Lan C, et al.
Pigment Cell Melanoma Res
. 2012 Mar;
25(3):E1-13.
PMID: 22417114
During the 2011 International Pigment Cell Conference (IPCC), the Vitiligo European Taskforce (VETF) convened a consensus conference on issues of global importance for vitiligo clinical research. As suggested by an...
3.
Schallreuter K, Bahadoran P, Picardo M, Slominski A, Elassiuty Y, Kemp E, et al.
Exp Dermatol
. 2008 Jan;
17(2):139-40.
PMID: 18205713
The pathobiology of vitiligo has been hotly disputed for as long as one remembers, and has been a magnet for endless speculation. Evidently, the different schools of thought--ranging, e.g. from...
4.
Le Poole I, Stennett L, Bonish B, Dee L, Robinson J, Hernandez C, et al.
Br J Dermatol
. 2003 Nov;
149(4):739-48.
PMID: 14616364
Background: Detection of CDw60 in skin is representative of ganglioside D3 expression. This ganglioside is expressed primarily by melanocytes, and is of interest as a membrane antigen targeted by immunotherapy...
5.
Le Poole I, Sarangarajan R, Zhao Y, Stennett L, Brown T, Sheth P, et al.
Pigment Cell Res
. 2002 Jan;
14(6):475-84.
PMID: 11775060
To define genes associated with the pigmentary disorder vitiligo, gene expression was compared in non-lesional melanocytes cultured from three vitiligo patients and from three control melanocyte cultures by differential display....
6.
Minwalla L, Zhao Y, Le Poole I, Wickett R, Boissy R
J Invest Dermatol
. 2001 Aug;
117(2):341-7.
PMID: 11511313
Melanosomes in keratinocytes of Black skin are larger and distributed individually whereas those within keratinocytes of Caucasian skin are smaller and distributed in clusters. This disparity contributes to differences in...
7.
Minwalla L, Zhao Y, Cornelius J, Babcock G, Wickett R, Le Poole I, et al.
Pigment Cell Res
. 2001 Jul;
14(3):185-94.
PMID: 11434566
We propose that some of the critical molecules involved in the transfer of melanosomes from melanocytes to keratinocytes include plasma membrane lectins and their glycoconjugates. To investigate this mechanism, co-cultures...
8.
Das P, van den Wijngaard R, Le Poole I
Trends Immunol
. 2001 Apr;
22(3):130-6.
PMID: 11286727
Vitiligo is a skin disease in which melanocytes (MCs) are eradicated from lesional epidermis, resulting in disfiguring loss of pigment. MCs are destroyed by MC-reactive T cells, as well as...
9.
van den Wijngaard R, Aten J, Scheepmaker A, Le Poole I, Tigges A, Westerhof W, et al.
Br J Dermatol
. 2000 Sep;
143(3):573-81.
PMID: 10971331
Although the aetiology of the hypopigmentary disorder vitiligo is ill understood, it is clear that pigment producing cells are absent from vitiliginous lesional skin. The present study was designed to...
10.
Le Poole I, Boissy R, Sarangarajan R, Chen J, Forristal J, Sheth P, et al.
In Vitro Cell Dev Biol Anim
. 2000 Aug;
36(5):309-19.
PMID: 10937834
Vitiligo is an enigmatic pigmentary disorder of the skin. Factors potentially involved in the progressive loss of melanocytes from the basal layer of the epidermis include genetically determined aberrancies of...