I B Borecki
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Explore the profile of I B Borecki including associated specialties, affiliations and a list of published articles.
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85
Citations
765
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Recent Articles
1.
Olfson E, Saccone N, Johnson E, Chen L, Culverhouse R, Doheny K, et al.
Mol Psychiatry
. 2015 Aug;
21(5):601-7.
PMID: 26239294
The common nonsynonymous variant rs16969968 in the α5 nicotinic receptor subunit gene (CHRNA5) is the strongest genetic risk factor for nicotine dependence in European Americans and contributes to risk in...
2.
Frazier-Wood A, Kabagambe E, Wojczynski M, Borecki I, Tiwari H, Smith C, et al.
Nutr Metab Cardiovasc Dis
. 2013 Mar;
23(11):1154-8.
PMID: 23484911
Background And Aims: In vitro studies suggest that low density lipoprotein receptor-related protein 1 (LRP1) plays a role in the secondary uptake of chylomicrons. In addition, in vivo studies using...
3.
Smith C, Ngwa J, Tanaka T, Qi Q, Wojczynski M, Lemaitre R, et al.
Int J Obes (Lond)
. 2013 Jan;
37(9):1211-20.
PMID: 23357958
Objective: Low-density lipoprotein-related receptor protein 1 (LRP1) is a multi-functional endocytic receptor and signaling molecule that is expressed in adipose and the hypothalamus. Evidence for a role of LRP1 in...
4.
Aslibekyan S, An P, Frazier-Wood A, Kabagambe E, Irvin M, Straka R, et al.
Nutr Metab Cardiovasc Dis
. 2012 Nov;
23(10):987-94.
PMID: 23149075
Background And Aims: Adiponectin is an adipose-secreted protein that has been linked to changes in insulin sensitivity, high-density lipoprotein cholesterol levels, and inflammatory patterns. Although fenofibrate therapy can raise adiponectin...
5.
Frazier-Wood A, Ordovas J, Straka R, Hixson J, Borecki I, Tiwari H, et al.
Pharmacogenomics J
. 2012 May;
13(4):312-7.
PMID: 22547144
As a peroxisome proliferator-activated receptor alpha (PPARα) agonist, fenofibrate favorably modulates dyslipidemia and inflammation markers, which are associated with cardiovascular risk. To determine whether variation in the PPARα receptor gene...
6.
Graff M, North K, Franceschini N, Reiner A, Feitosa M, Carr J, et al.
Int J Obes (Lond)
. 2012 May;
37(3):432-8.
PMID: 22546774
Background: Fatty liver disease (FLD) is characterized by increased intrahepatic triglyceride content with or without inflammation and is associated with obesity, and features of the metabolic syndrome. Several recent genome-wide...
7.
Wood A, Kabagambe E, Borecki I, Tiwari H, Ordovas J, Arnett D
Lipid Insights
. 2011 Sep;
2011(4):7-15.
PMID: 21912485
We aimed to investigate the relationship between dietary saturated fat on fasting triglyceride (TG) and cholesterol levels, and any mediation of this relationship by dietary carbohydrate intake. Men and women...
8.
Wilk J, Laramie J, Latourelle J, Williamson S, Nagle M, Tobin J, et al.
Int J Obes (Lond)
. 2008 Mar;
32(6):930-5.
PMID: 18317470
Objective: The NHLBI Family Heart Study (FHS) genome-wide linkage scan identified a region of chromosome 7q with a logarithm of odds score of 4.9 for body mass index (BMI). Design:...
9.
North K, Carr J, Borecki I, Kraja A, Province M, Pankow J, et al.
Atherosclerosis
. 2006 Sep;
193(1):11-9.
PMID: 16965775
Background: Calcified coronary plaque (CCP) is a complex trait influenced by both genes and environment, and plausibly an interaction between the two. Because the familial aggregation of CCP has been...
10.
Avery C, Freedman B, Kraja A, Borecki I, Miller M, Pankow J, et al.
Diabetologia
. 2006 Aug;
49(10):2329-36.
PMID: 16906437
Aims/hypothesis: While there are sex-related differences in both the prevalence of type 2 diabetes mellitus and disease risk factors, there is only limited research on sex-specific influences on type 2...