I Akiguchi
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Explore the profile of I Akiguchi including associated specialties, affiliations and a list of published articles.
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Articles
337
Citations
2605
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Recent Articles
1.
Kawamoto Y, Ito H, Kobayashi Y, Suzuki Y, Akiguchi I, Fujimura H, et al.
Neuropathol Appl Neurobiol
. 2010 Mar;
36(4):331-44.
PMID: 20202124
Aims: HtrA2/Omi is a mitochondrial serine protease that promotes the apoptotic processes, but the relationship between HtrA2/Omi and amyotrophic lateral sclerosis (ALS) is still unknown. The purpose of the present...
2.
Akiguchi I, Tomimoto H, Wakita H, Yamamoto Y, Suenaga T, Ueno M, et al.
Neuropathology
. 2009 Jun;
19(1):119-28.
PMID: 19519655
Binswanger's disease (BD) is a condition characterized by prominent brain atrophy with ventricular dilatation, diffuse white matter (WM) lesions and a scattering of lacunar infarcts. BD patients have dementia, and...
3.
Honjo Y, Shirakashi Y, Kawamoto Y, Akiguchi I
Clin Neuropathol
. 2008 Sep;
27(5):309-16.
PMID: 18808062
MSA is a neurodegenerative disease and GCIs are specific pathological hallmarks in the brain of MSA patients. Recently, Cdk5 immunopositive GCIs were reported, but the function of Cdk5 in the...
4.
Ueno M, Akiguchi I, Hosokawa M, Shinnou M, Sakamoto H, Takemura M, et al.
Arch Gerontol Geriatr
. 2008 Jul;
25(3):321-31.
PMID: 18653120
Brain transfer rate (BTR) and brain to plasma concentration ratio (BPCR) of radiolabelled human serum albumin injected intravenously were calculated to evaluate the brain transfer of serum albumin in the...
5.
Yamamoto Y, Akiguchi I, Oiwa K, Hayashi M, Ohara T, Ozasa K
Cerebrovasc Dis
. 2005 Mar;
19(5):302-8.
PMID: 15775671
Background: Twenty-four-hour blood pressure (BP) readings have been found to correlate with hypertensive target organ damage. Lacunar infarcts (LI) and white matter lesions (WML) probably represent manifestations of cerebral hypertensive...
6.
Mizutani K, Oka N, Kaji R, Matsui M, Asanuma K, Kubori T, et al.
Eur Neurol
. 2005 Mar;
53(2):64-7.
PMID: 15753615
We analyzed the CD16+CD57- lymphocyte subset, which is considered to have strong natural killer (NK) cell activity, in peripheral blood from patients with chronic immune-mediated neuropathies and patients with other...
7.
Satoi H, Tomimoto H, Ohtani R, Kitano T, Kondo T, Watanabe M, et al.
Neuroscience
. 2004 Dec;
130(3):657-66.
PMID: 15590150
Accumulating evidences indicate that ceramide is closely involved in apoptotic cell death in neurodegenerative disorders and aging. We examined ceramide levels in the cerebrospinal fluid (CSF) or brain tissues from...
8.
Tomimoto H, Ihara M, Wakita H, Ohtani R, Lin J, Akiguchi I, et al.
Acta Neuropathol
. 2003 Sep;
106(6):527-34.
PMID: 13680276
Cerebrovascular white matter lesions represent an age-related neurodegenerative condition that appears as a hyperintense signal on magnetic resonance images. These lesions are frequently observed in aging, hypertension and cerebrovascular disease,...
9.
Watanabe T, Akiguchi I, Yagi H, Onishi K, Kawasaki T, Shiino A, et al.
Ann N Y Acad Sci
. 2002 Dec;
977:423-9.
PMID: 12480782
No abstract available.
10.
Wanschit J, Nakano S, Goudeau B, Strobel T, Rinner W, Wimmer G, et al.
Clin Neuropathol
. 2002 Oct;
21(5):220-31.
PMID: 12365725
Myofibrillar or desmin-related myopathies encompass neuromuscular disorders with abnormal deposits of desmin and myofibrillar alterations. We report 3 unrelated patients presenting with proximal and distal myopathy, and, as a unique...