I A Schepetkin
Overview
Explore the profile of I A Schepetkin including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
84
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Recent Articles
1.
Molecular Mechanisms for Regulation of Neutrophil Apoptosis under Normal and Pathological Conditions
Noseykina E, Schepetkin I, Atochin D
J Evol Biochem Physiol
. 2021 Jul;
57(3):429-450.
PMID: 34226754
Neutrophils are one of the main cells of innate immunity that perform a key effector and regulatory function in the development of the human inflammatory response. Apoptotic forms of neutrophils...
2.
Crocetti L, Quinn M, Schepetkin I, Giovannoni M
Expert Opin Ther Pat
. 2019 Jun;
29(7):555-578.
PMID: 31204543
Introduction: Human neutrophil elastase (HNE) is involved in a variety of serious chronic diseases, especially cardiopulmonary pathologies. For this reason, the regulation of HNE activity represents a promising therapeutic approach,...
3.
Shvedova M, Anfinogenova Y, Schepetkin I, Atochin D
Ross Fiziol Zh Im I M Sechenova
. 2018 Sep;
103(3):268-83.
PMID: 30199207
The article reviews the literature regarding the role of c-Jun-N-terminal kinases (JNK) and its inhibitors in brain damage in the settings of ischemia and reperfusion injury. The implication of JNK...
4.
Schepetkin I, Khlebnikov A, Giovannoni M, Kirpotina L, Cilibrizzi A, Quinn M
Curr Med Chem
. 2013 Dec;
21(13):1478-504.
PMID: 24350845
Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) expressed on a variety of cell types. These receptors play an important role in the regulation of inflammatory reactions and sensing...
5.
Avrova N, Zakharova I, Tyurin V, Tyurina Y, Gamaley I, Schepetkin I
Neurochem Res
. 2002 Oct;
27(7-8):751-9.
PMID: 12374210
The metabolic effects of ganglioside GM1 were found to be quite different in brain synaptosomes and phagocytic cells. Incubation of rat brain cortex synaptosomes with GM1 was shown to decrease...
6.
Schepetkin I, Cherdyntseva N, Kagiya V
Pathophysiology
. 2001 Nov;
8(2):119-127.
PMID: 11720808
The influence of sanazole and metronidazole on cytochrome C (Cyt c(3+)) reduction in the enzyme systems xanthine/xanthine oxidase and NADPH-cytochrome P450 reductase was studied. The addition of sanazole but not...
7.
Schepetkin I
IUBMB Life
. 2000 Jan;
48(5):499-504.
PMID: 10637765
The lucigenin luminescence elicited by rat liver microsomes and its modulation by the nitroazole compounds metronidazole and sanazole (drug AK-2123), as well as the rates of lucigenin-dependent NADPH consumption and...
8.
Schepetkin I
Biochemistry (Mosc)
. 1999 Feb;
64(1):25-32.
PMID: 9986909
NADPH oxidation and cytochrome c reduction with and without lucigenin as well as NAD(P)H/lucigenin-dependent chemiluminescence of rat liver microsomes were studied. An increased rate of NADPH oxidation and cytochrome c...
9.
Schepetkin I, Cherdyntseva N, Borunov E, Skutina I, Naumov S
J Cancer Res Clin Oncol
. 1991 Jan;
117(2):172-4.
PMID: 1848861
Production of reactive oxygen species by neutrophils was analyzed by a chemiluminometric method in the presence of luminol in ten healthy donors, eight patients with gastric cancer and ten patients...