I A Iachine
Overview
Explore the profile of I A Iachine including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
435
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Recent Articles
1.
Yashin A, De Benedictis G, Vaupel J, Tan Q, Andreev K, Iachine I, et al.
J Gerontol A Biol Sci Med Sci
. 2000 Jul;
55(7):B319-28.
PMID: 10898245
In population studies of aging, the data on genetic markers are often collected for individuals from different age groups. The idea of such studies is to identify "longevity" or "frailty"...
2.
Begun A, Iachine I, Yashin A
Twin Res
. 2000 May;
3(1):51-7.
PMID: 10808241
The traditional frailty models used in genetic analysis of bivariate survival data assume that individual frailty (and longevity) is influenced by thousands of genes, and that the contribution of each...
3.
Yashin A, Begun A, Iachine I
J Epidemiol Biostat
. 1999 Dec;
4(1):53-60.
PMID: 10613717
Background: Molecular epidemiological studies of aging and longevity are focused on evaluating the effects of single genes on susceptibility to disease and death. The effects of all genetic factors on...
4.
Yashin A, De Benedictis G, Vaupel J, Tan Q, Andreev K, Iachine I, et al.
Am J Hum Genet
. 1999 Sep;
65(4):1178-93.
PMID: 10486337
In population studies on aging, the data on genetic markers are often collected for individuals from different age groups. The purpose of such studies is to identify, by comparison of...
5.
Yashin A, Iachine I, Harris J
Behav Genet
. 1999 Jun;
29(1):11-9.
PMID: 10371754
Molecular epidemiological studies confirm tremendous variability in genetic and environmental susceptibility to disease and death for humans. This variability as well as the roles of genetic and environmental factors in...
6.
What difference does the dependence between durations make? Insights for population studies of aging
Yashin A, Iachine I
Lifetime Data Anal
. 1999 Apr;
5(1):5-22.
PMID: 10213999
The interpretation of age-specific changes in hazards, relative risks, genetic parameters and other indicators of aging calculated from data on related individuals should take into account the regularities of bivariate...
7.
Iachine I, Holm N, Harris J, Begun A, Iachina M, Laitinen M, et al.
Twin Res
. 1999 Apr;
1(4):196-205.
PMID: 10100811
Molecular epidemiological studies confirm a substantial contribution of individual genes to variability in susceptibility to disease and death for humans. To evaluate the contribution of all genes to susceptibility and...
8.
Yashin A, Iachine I, Christensen K, Holm N, Vaupel J
Behav Genet
. 1998 Jul;
28(3):207-14.
PMID: 9670596
The presence of familial and genetic effects in the Activities-of-Daily-Life (ADL) data collected in the first wave of the 1995 Longitudinal Study of Aging of Danish Twins (LSADT) older than...
9.
Vaupel J, Carey J, Christensen K, Johnson T, Yashin A, Holm N, et al.
Science
. 1998 May;
280(5365):855-60.
PMID: 9599158
Old-age survival has increased substantially since 1950. Death rates decelerate with age for insects, worms, and yeast, as well as humans. This evidence of extended postreproductive survival is puzzling. Three...
10.
Yashin A, Iachine I
Demography
. 1997 Feb;
34(1):31-48.
PMID: 9074830
In this paper we discuss an approach to the analysis of mortality and longevity limits when survival data on related individuals with and without observed covariates are available. The approach...