Hyung W Nam
Overview
Explore the profile of Hyung W Nam including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
184
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0
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Recent Articles
1.
Endothelial Neurogranin Regulates Blood-Brain Barrier Permeability via Modulation of the AKT Pathway
Akande A, Carter Z, Stokes K, Nam H
Mol Neurobiol
. 2024 Oct;
62(4):3991-4007.
PMID: 39367201
Neurogranin (Ng) expression is a biomarker for Alzheimer's disease. A loss of brain Ng and an increase in CSF Ng positively correlate with cognitive decline. Ng is known to regulate...
2.
Chesnokova L, Mosher B, Fulkerson H, Nam H, Shakya A, Yurochko A
Proc Natl Acad Sci U S A
. 2024 Mar;
121(12):e2312290121.
PMID: 38483999
Human cytomegalovirus (HCMV) infection of monocytes is essential for viral dissemination and persistence. We previously identified that HCMV entry/internalization and subsequent productive infection of this clinically relevant cell type is...
3.
Jorgensen A, Rashdan N, Rao K, Delgadillo L, Kolluru G, Krzywanski D, et al.
Redox Biol
. 2024 Feb;
70:103085.
PMID: 38359746
Endothelial dysfunction and endothelial activation are common early events in vascular diseases and can arise from mitochondrial dysfunction. Neurogranin (Ng) is a 17kD protein well known to regulate intracellular Ca-calmodulin...
4.
Jorgensen A, Abdullah C, Bhuiyan M, Watt M, Dominic P, Kolluru G, et al.
Exp Mol Pathol
. 2022 Jul;
127:104815.
PMID: 35870494
Intracellular Ca-calmodulin (CaM) signaling plays an important role in Ca-CaM-dependent kinase (CaMKII) and calcineurin (CaN)-mediated cardiac biology. While neurogranin (Ng) is known as a major Ca-CaM modulator in the brain,...
5.
Nahar L, Kaufman S, Davis P, Saunders S, Disbrow E, Patterson J, et al.
Transl Psychiatry
. 2022 Feb;
12(1):71.
PMID: 35194024
As of 2018, 14.4 million adults ages 18 and older in the U.S had alcohol use disorder (AUD). However, only about 8% of adults who had AUD in the past...
6.
Nahar L, Delacroix B, Nam H
Front Psychiatry
. 2021 Jul;
12:679960.
PMID: 34220586
While great progress has been made in the understanding of neurological illnesses, the pathologies, and etiologies that give rise to these diseases still remain an enigma, thus, also making treatments...
7.
Nahar L, Grant C, Hewett C, Cortes D, Reker A, Kang S, et al.
J Neurochem
. 2020 Jun;
156(2):212-224.
PMID: 32594517
The corticostriatal circuitry and its glutamate-γ-aminobuturic acid (GABA) interactions play an essential role in regulating neuronal excitability during reward-seeking behavior. However, the contribution of GABAergic interneurons in the corticostriatal circuitry...
8.
Cheriyan V, Alfaidi M, Jorgensen A, Alam M, Abdullah C, Kolluru G, et al.
Redox Biol
. 2020 Mar;
34:101487.
PMID: 32173345
Endothelial nitric oxide (NO) is a critical mediator of vascular function and vascular remodeling. NO is produced by endothelial nitric oxide synthase (eNOS), which is activated by calcium (Ca)-dependent and...
9.
Nam H, Grant C, Jorgensen A, Holtz-Heppelmann C, Trutschl M, Cvek U
Proteomics
. 2019 Dec;
20(1):e1900266.
PMID: 31814311
Dysfunction of glutamate neurotransmission in the nucleus accumbens (NAc) has been implicated in the pathophysiology of alcohol use disorders (AUD). Neurogranin (Ng) is exclusively expressed in the brain and mediates...
10.
Sullivan 3rd J, Grant C, Reker A, Nahar L, Goeders N, Nam H
Neuropharmacology
. 2019 Mar;
150:91-99.
PMID: 30902751
Glutamate dysregulation is known to contribute to many psychiatric disorders including schizophrenia. Aberrant cortico-striatal activity and therefore glutamate levels might be relevant to this disease characterized by reduced prepulse inhibition...