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Hyun Kook Lim

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Articles 106
Citations 815
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Recent Articles
11.
Kim S, Wang S, Kang D, Um Y, Yoon H, Lee S, et al.
Alzheimers Dement . 2024 Jun; 20(7):4868-4878. PMID: 38889242
Introduction: Despite prior research on the association between sarcopenia and cognitive impairment in the elderly, a comprehensive model that integrates various brain pathologies is still lacking. Methods: We used data...
12.
Wang S, Kang D, Um Y, Kim S, Lee S, Lee C, et al.
Psychiatry Investig . 2024 May; 21(5):449-456. PMID: 38810993
Objective: The rising prevalence of mild cognitive impairment (MCI) has spurred interest in innovative cognitive rehabilitation approaches, including serious games. This review summarizes randomized clinical trials (RCTs) exploring the impact...
13.
Lee M, Kim H, Choe Y, Yang H, Lee J, Lee H, et al.
Sci Rep . 2024 May; 14(1):12276. PMID: 38806509
Alzheimer's disease (AD) accounts for 60-70% of the population with dementia. Mild cognitive impairment (MCI) is a diagnostic entity defined as an intermediate stage between subjective cognitive decline and dementia,...
14.
Um Y, Wang S, Kang D, Kim S, Lee C, Kim D, et al.
J Alzheimers Dis . 2024 Apr; 99(2):705-714. PMID: 38669549
Background: Recent interest has surged in the locus coeruleus (LC) for its early involvement in Alzheimer's disease (AD), notably concerning the apolipoprotein ɛ4 allele (APOE4). Objective: This study aimed to...
15.
Kim T, Kang D, Salazar Fajardo J, Jang H, Um Y, Kim S, et al.
Front Neurol . 2024 Apr; 15:1356073. PMID: 38660096
Introduction: Transcranial direct current stimulation (tDCS) may effectively preserve and improve cognitive function in patients with mild cognitive impairment (MCI). Research has shown that Individual brain characteristics can influence the...
16.
Wang S, Kim S, Choi W, Lim H, Woo Y, Pae C, et al.
Clin Psychopharmacol Neurosci . 2024 Apr; 22(2):222-231. PMID: 38627070
Previous studies suggested effectiveness of psilocybin in the field of mental health. FDA designated psilocybin as a "breakthrough therapy" for the treatment of treatment-resistant depression (TRD) in 2018. This paper...
17.
Wang S, Kang D, Um Y, Kim S, Lee C, Scheltens P, et al.
Alzheimers Res Ther . 2024 Mar; 16(1):55. PMID: 38468313
Background: Multimer detection system-oligomeric amyloid-β (MDS-OAβ) is a measure of plasma OAβ, which is associated with Alzheimer's disease (AD) pathology. However, the relationship between MDS-OAβ and disease severity of AD...
18.
Kim S, Wang S, Kang D, Um Y, Yang H, Lee H, et al.
Psychiatry Investig . 2024 Jan; 21(1):37-43. PMID: 38281737
Objective: We aimed to create an efficient and valid predicting model which can estimate individuals' brain age by quantifying their regional brain volumes. Methods: A total of 2,560 structural brain...
19.
Kim J, Kim S, Um Y, Wang S, Kim R, Choe Y, et al.
Clin Psychopharmacol Neurosci . 2024 Jan; 22(1):169-181. PMID: 38247423
Objective: : Cognitive reserve has emerged as a concept to explain the variable expression of clinical symptoms in the pathology of Alzheimer's disease (AD). The association between years of education,...
20.
Choi I, Wang S, Um Y, Lim H, Lee C, Kang D
Psychiatry Investig . 2024 Jan; 20(12):1177-1184. PMID: 38163657
Objective: We aimed to evaluate the impact of interaction between APOE ε4 carrier status and body composition measurements on intra- and inter-regional functional connectivity (FC) in mild cognitive impairment (MCI)...