Hyun-Kyu An
Overview
Explore the profile of Hyun-Kyu An including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
309
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0
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Recent Articles
1.
Jeong S, An H, Ha S, Yu S
Int J Mol Sci
. 2023 May;
24(9).
PMID: 37175992
Autophagy is a cellular catabolic process that degrades and recycles cellular materials. Autophagy is considered to be beneficial to the cell and organism by preventing the accumulation of toxic protein...
2.
Nam H, Lee Y, Kim B, Lee J, Hwang S, An H, et al.
Nat Commun
. 2022 Apr;
13(1):1972.
PMID: 35418126
Hyperimmunity drives the development of Alzheimer disease (AD). The immune system is under the circadian control, and circadian abnormalities aggravate AD progress. Here, we investigate how an AD-linked mutation deregulates...
3.
Ryu H, Kim L, Jeong H, Yeo B, Lee J, Nam H, et al.
Exp Mol Med
. 2021 Mar;
53(3):369-383.
PMID: 33654220
Unc-51-like autophagy activating kinase 1 (ULK1), a mammalian homolog of the yeast kinase Atg1, has an essential role in autophagy induction. In nutrient and growth factor signaling, ULK1 activity is...
4.
Kim E, Jeon S, An H, Kianpour M, Yu S, Kim J, et al.
Sci Adv
. 2020 Sep;
6(39).
PMID: 32978164
There has been a great deal of interest in the development of technologies for actively manipulating neural networks in vitro, providing natural but simplified environments in a highly reproducible manner...
5.
Hong C, Yeon J, Yeo B, Woo H, An H, Heo W, et al.
FASEB J
. 2020 Jan;
34(1):161-179.
PMID: 31914609
Fas-apoptotic inhibitory molecule 2 (FAIM2) is a member of the transmembrane BAX inhibitor motif-containing (TMBIM) family. TMBIM family is comprised of six anti-apoptotic proteins that suppress cell death by regulating...
6.
An H, Chung K, Park H, Hong J, Gim J, Choi H, et al.
Autophagy
. 2019 Dec;
16(9):1598-1617.
PMID: 31818185
Abbreviations: AA: amino acid; ACD: autophagic cell death; ACTB: actin beta; ANXA5: annexin A5; APAF1: apoptotic peptidase activating factor 1; Atg: autophagy related; ATG16L1: autophagy related 16 like 1; BafA:...
7.
Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al.
Autophagy
. 2019 Jun;
16(3):512-530.
PMID: 31234698
Macroautophagy/autophagy is generally regarded as a cytoprotective mechanism, and it remains a matter of controversy whether autophagy can cause cell death in mammals. Here, we show that chronic restraint stress...
8.
Park H, Chung K, An H, Gim J, Hong J, Woo H, et al.
Front Mol Neurosci
. 2019 Mar;
12:46.
PMID: 30853892
Regulated cell death (RCD) plays a fundamental role in human health and disease. Apoptosis is the best-studied mode of RCD, but the importance of other modes has recently been gaining...
9.
Yoon H, An H, Ko M, Kim K, Mun S, Kim D, et al.
Int J Mol Sci
. 2016 Aug;
17(8).
PMID: 27490539
In this research, we firstly demonstrated that physcion, an anthraquinone derivative, specifically increased the expression of the human α2,8-sialyltransferase (hST8Sia VI) gene in SK-N-BE(2)-C human neuroblastoma cells. To establish the...
10.
Chung K, Jeong E, Park H, An H, Yu S
Front Cell Neurosci
. 2016 May;
10:116.
PMID: 27199668
Cytoplasmic Ca(2+) actively engages in diverse intracellular processes from protein synthesis, folding and trafficking to cell survival and death. Dysregulation of intracellular Ca(2+) levels is observed in various neuropathological states...