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Hyun-Keun Kim

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Articles 9
Citations 376
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Recent Articles
1.
Lee J, Ha D, Go H, Youn J, Kim H, Jin R, et al.
Int J Mol Sci . 2020 Jul; 21(13). PMID: 32635660
Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or failure, leading to the death of patients within a few hours or days. Previous studies...
2.
Lim S, Kim H, Lee W, Kim S
Heliyon . 2020 Jul; 6(6):e04267. PMID: 32613128
Benign prostatic hyperplasia (BPH) is one of the most frequently observed diseases in the elderly male population worldwide. A variety of factors such as aging, hormonal imbalance, chronic inflammation, and...
3.
Ha D, Kim H, Lee J, Kwon H, Park G, Yang S, et al.
Cells . 2020 May; 9(5). PMID: 32392899
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication. With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the characteristics of producer cells, exosomes can...
4.
Shin K, Ha D, Kim J, Crumrine D, Meyer J, Wakefield J, et al.
Cells . 2020 Mar; 9(3). PMID: 32164386
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells...
5.
Kim H, Lim S, Bae M, Lee W, Kim S
Mediators Inflamm . 2019 Mar; 2019:6085801. PMID: 30918469
IL-37 is an immunomodulatory cytokine that suppresses inflammation in various cell types and disease models. However, its role in keratinocytes has not been clearly understood, and there has been no...
6.
Kim H, Bae M, Lim S, Lee W, Kim S
Nutrients . 2018 Oct; 10(10). PMID: 30279326
Psoriasis is a chronic inflammatory disease with complex etiology involving multiple factors. Current treatment methods are highly limited and there is a strong need for the development of safer and...
7.
Lee W, Ko K, Kim H, Lee D, Nam I, Lim S, et al.
J Nat Prod . 2018 Jun; 81(6):1343-1356. PMID: 29869503
Estrogen deficiency after menopause increases bone loss by activating RANKL-induced osteoclast differentiation. Dehydrodiconiferyl alcohol (DHCA), a lignan originally isolated from Cucurbita moschata, has been thought to be a phytoestrogen based...
8.
Bae M, Choi J, Kim H, Lim S, Kim S
Phytomedicine . 2018 May; 43:150-157. PMID: 29747748
Background: PG201 is a botanical formulation, approved as an ethical drug (ETC) phytomedicine for treatment of patients with osteoarthritis in Korea, following satisfactory phase II and phase III studies. This...
9.
Lee W, Ko K, Kim H, Lim S, Kim S
Biochem Biophys Res Commun . 2017 Dec; 495(3):2242-2248. PMID: 29253565
Estrogen deficiency results in an imbalance between the levels of bone-resorping osteoclasts and bone-forming osteoblasts, eventually leading to overall bone loss. Dehydrodiconiferyl alcohol (DHCA), a lignan compound originally isolated from...