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Hyun-Jin An

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Articles 36
Citations 561
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Recent Articles
1.
Gwon M, Leem J, An H, Gu H, Bae S, Kim J, et al.
Mol Ther Nucleic Acids . 2023 Oct; 34:102036. PMID: 37799329
Atopic dermatitis (AD) is a common inflammatory skin disease caused by an immune disorder. Mast cells are known to be activated and granulated to maintain an allergic reaction, including rhinitis,...
2.
An H, Gwon M, Gu H, Bae S, Leem J, Lee J, et al.
Int J Mol Med . 2023 Apr; 51(5). PMID: 37026512
Atherosclerosis is a progressive chronic inflammatory condition that is the cause of most cardiovascular and cerebrovascular diseases. The transcription factor nuclear factor‑κB (NF‑κB) regulates a number of genes involved in...
3.
Gu H, An H, Gwon M, Bae S, Zouboulis C, Park K
Biomolecules . 2022 Dec; 12(12). PMID: 36551286
Acne vulgaris has a pathogenesis that involves increased sebum production and perifollicular inflammation. Sterol regulatory element-binding protein-1 (SREBP-1) and peroxisome proliferator activated receptor-γ (PPAR-γ) are transcription factors that regulate numerous...
4.
Bae S, Gu H, Gwon M, An H, Han S, Lee S, et al.
Toxins (Basel) . 2022 Oct; 14(10). PMID: 36287932
() bacteria cause almost all primary skin infections in humans. Bee venom (BV) and melittin (Mel) have multiple effects, including antibacterial and anti-inflammatory activities. This study aims to demonstrate their...
5.
Kim Y, Gu H, Gwon M, An H, Bae S, Leem J, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36232665
The global burden of chronic kidney disease is increasing, and the majority of these diseases are progressive. Special site-targeted drugs are emerging as alternatives to traditional drugs. Oligonucleotides (ODNs) have...
6.
Gu H, An H, Gwon M, Bae S, Leem J, Lee S, et al.
Int J Mol Sci . 2022 Mar; 23(6). PMID: 35328573
Acne vulgaris is the most common disease of the pilosebaceous unit. The pathogenesis of this disease is complex, involving increased sebum production and perifollicular inflammation. Understanding the factors that regulate...
7.
Jung H, An H, Gwon M, Gu H, Bae S, Lee S, et al.
Molecules . 2022 Feb; 27(3). PMID: 35164031
Renal fibrosis is a common process of various kidney diseases. Autophagy is an important cell biology process to maintain cellular homeostasis. In addition, autophagy is involved in the pathogenesis of...
8.
Gwon M, An H, Gu H, Kim Y, Han S, Park K
J Mol Med (Berl) . 2021 May; 99(9):1265-1277. PMID: 34031696
Renal fibrosis is a progressive and chronic process that influences kidneys with chronic kidney disease (CKD), irrespective of cause, leading to irreversible failure of renal function and end-stage kidney disease....
9.
Kim Y, Kim H, Gwon M, Gu H, An H, Bae S, et al.
Biomedicines . 2021 Apr; 9(4). PMID: 33806080
Autophagy in the proximal tubules may promote fibrosis by activating tubular cell death, interstitial inflammation, and the production of pro-fibrotic factors. The signal transducer and activator of transcription 3 (STAT3)...
10.
An H, Kim J, Gwon M, Gu H, Kim H, Leem J, et al.
Int J Mol Sci . 2020 Jan; 21(2). PMID: 31952262
Hyperlipidemia is a chronic disorder that plays an important role in the development of cardiovascular diseases, type II diabetes, atherosclerosis, hypertension, and non-alcoholic fatty liver disease. Hyperlipidemias have created a...