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Hyun-Gug Jung

Explore the profile of Hyun-Gug Jung including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 98
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Recent Articles
1.
Kim A, Bae Y, Gadhe C, Jung H, Yang E, Kim H, et al.
iScience . 2025 Jan; 28(1):111587. PMID: 39811670
TWIK-1 belongs to the two-pore domain K (K2P) channel family, which plays an essential role in the background K conductance of cells. Despite the development of exon 2-deleted knockout (KO)...
2.
Usmani S, Jung H, Zhang Q, Kim M, Choi Y, Caglayan A, et al.
Nat Commun . 2024 Nov; 15(1):9419. PMID: 39482312
The hypothalamus plays an important role in aging, but it remains unclear regarding the underlying epigenetics and whether this hypothalamic basis can help address aging-related diseases. Here, by comparing mouse...
3.
Lee S, Lee J, Yang M, Kim D, Jung H, Ko D, et al.
Materials (Basel) . 2023 Feb; 16(3). PMID: 36770047
Recent advances in additive manufacturing have provided more freedom in the design of metal parts; hence, the prototyping of fluid machines featuring extremely complex geometries has been investigated extensively. The...
4.
Kim J, Jung H, Kim A, Shim H, Hyeon S, Lee Y, et al.
Cell Death Differ . 2021 Mar; 28(9):2571-2588. PMID: 33753902
Hevin, also known as SPARC-like protein 1 (SPARCL1 or SC1), is a synaptogenic protein secreted by astrocytes and modulates the formation of glutamatergic synapses in the developing brain by interacting...
5.
Jung H, Kim A, Kim S, Park J, Hwang E
Brain Sci . 2021 Jan; 11(1). PMID: 33440655
AEG-1, also called MTDH, has oncogenic potential in numerous cancers and is considered a multifunctional modulator because of its involvement in developmental processes and inflammatory and degenerative brain diseases. However,...
6.
Kim J, Afridi R, Han J, Jung H, Kim S, Hwang E, et al.
Brain . 2020 Dec; 144(2):528-552. PMID: 33382892
The complement system is part of the innate immune system that comprises several small proteins activated by sequential cleavages. The majority of these complement components, such as components 3a (C3a)...
7.
Bae Y, Choi J, Ryoo K, Kim A, Kwon O, Jung H, et al.
Int J Mol Sci . 2020 Dec; 21(24). PMID: 33348878
Astrocytes, the most abundant cell type in the brain, are non-excitable cells and play critical roles in brain function. Mature astrocytes typically exhibit a linear current-voltage relationship termed passive conductance,...
8.
Cho C, Lee S, Kim A, Yarishkin O, Ryoo K, Lee Y, et al.
EMBO Rep . 2019 Nov; 21(2):e48097. PMID: 31782602
TMEM16A, a Ca -activated Cl channel, is known to modulate the excitability of various types of cells; however, its function in central neurons is largely unknown. Here, we show the...
9.
Kim A, Jung H, Kim S, Choi M, Park J, Lee S, et al.
Cell Biochem Funct . 2019 Nov; 38(2):167-175. PMID: 31782179
TREK-1 (TWIK-related K+ channel), a member of the two-pore domain K+ (K2P) channel family, is highly expressed in astrocytes, where it plays a key role in glutamate release and passive...
10.
Kim A, Jung H, Kim Y, Kim S, Park J, Lee S, et al.
Int J Mol Sci . 2019 Nov; 20(23). PMID: 31771312
TWIK-related potassium channel-1 (TREK-1) is broadly expressed in the brain and involved in diverse brain diseases, such as seizures, ischemia, and depression. However, the cell type-specific roles of TREK-1 in...