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Hyeun Wook Chang

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Articles 148
Citations 1559
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Recent Articles
1.
Guragain D, Gurung P, Chang J, Katila N, Chang H, Jeong B, et al.
Biochim Biophys Acta Gen Subj . 2020 May; 1864(8):129631. PMID: 32418902
Background: AMP-activated protein kinase (AMPK) exerts its anti-inflammatory effects by suppressing redox-sensitive nuclear factor kappa B (NF-κB) and pro-inflammatory cytokines including TNF-α. However, it is unclear whether AMPK regulates anti-inflammatory...
2.
Li X, Lee Y, Jin F, Park Y, Deng Y, Kang Y, et al.
Sci Rep . 2020 Feb; 10(1):3552. PMID: 32080328
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
3.
Chang H, Kanegasaki S, Jin F, Deng Y, You Z, Chang J, et al.
Allergy . 2020 Jan; 75(6):1371-1381. PMID: 31954080
Background: Signal transduction pathways mediated by various receptors expressed on mast cells are thought to be complex, and inhibitory signals that turn off activating signals are not known. Methods: Upstream...
4.
Kwon E, Pathak D, Kim H, Dahal P, Ha S, Lee S, et al.
IUCrJ . 2019 Oct; 6(Pt 5):938-947. PMID: 31576226
The stressosome transduces environmental stress signals to SigB to upregulate SigB-dependent transcription, which is required for bacterial viability. The stressosome core is composed of RsbS and at least one of...
5.
Deng Y, Jin F, Li X, Park S, Chang J, Kim D, et al.
Int Immunopharmacol . 2019 Jun; 74:105702. PMID: 31228819
Sauchinone, the biologically active lignan of Saururus chinensis, has been reported to have anti-inflammatory, antitumor, antioxidant, and hepatoprotective properties. However, little is known about the effect of sauchinone on FcεRI-mediated...
6.
Timilshina M, You Z, Lacher S, Acharya S, Jiang L, Kang Y, et al.
Cell Rep . 2019 Jun; 27(10):2948-2961.e7. PMID: 31167140
The function of regulatory T (T) cells depends on lipid oxidation. However, the molecular mechanism by which T cells maintain lipid metabolism after activation remains elusive. Liver kinase B1 (LKB1)...
7.
Kwon E, Li X, Deng Y, Chang H, Kim D
FASEB J . 2019 Feb; 33(5):6539-6550. PMID: 30807229
As a master regulator for metabolic and energy homeostasis, AMPK controls the activity of metabolic enzymes and transcription factors in response to cellular ATP status. AMPK has been thus recognized...
8.
Jin F, Li X, Deng Y, Timilshina M, Huang B, Kim D, et al.
Allergy . 2018 Dec; 74(6):1145-1156. PMID: 30565708
Background: Nuclear receptor subfamily 4 group A member 1 (NR4A1), an orphan nuclear receptor, has been implicated in several biological events such as metabolism, apoptosis, and inflammation. Recent studies indicate...
9.
Ha S, Kwon K, Park J, Abekura F, Lee Y, Chung T, et al.
J Cell Biochem . 2018 Dec; 120(6):9810-9819. PMID: 30525244
A water-soluble saponin, Esculentoside H (EsH), 3-O-(O-β-d-glucopyranosyl-(1→4)-β-d-xylopyranosyl)-28-β-d-glucopyranosylphytolaccagenin has been isolated and purified from the root extract of perennial plant Phytolacca esculenta. EsH is known to be an anticancer compound, having...
10.
Kim G, Li X, Kim S, Yang I, Hahn D, Chin J, et al.
Org Lett . 2018 Nov; 20(23):7539-7543. PMID: 30456957
Six seongsanamides were isolated from the culture broth of Bacillus safensis KCTC 12796BP, and their structures were elucidated by spectroscopic data analysis combined with Marfey's method, electronic circular dichroism calculations,...