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Hwei-Jan Hsu

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Articles 38
Citations 786
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Recent Articles
1.
Huang W, Kajal K, Wibowo R, Amartuvshin O, Kao S, Rastegari E, et al.
Development . 2023 Dec; 151(1). PMID: 38063853
High-sugar diets (HSDs) often lead to obesity and type 2 diabetes, both metabolic syndromes associated with stem cell dysfunction. However, it is unclear whether excess dietary sugar affects stem cells....
2.
Fang C, Kuo H, Amartuvshin O, Hsu H, Liu S, Yao J, et al.
Cell Death Discov . 2023 Jan; 9(1):4. PMID: 36617578
Tubulin s-palmitoylation involves the thioesterification of a cysteine residue in tubulin with palmitate. The palmitate moiety is produced by the fatty acid synthesis pathway, which is rate-limited by acetyl-CoA carboxylase...
3.
Lin C, Lin T, Hsu S, Hsu H
FEBS Open Bio . 2022 Nov; 12(12):2102-2110. PMID: 36331359
Recent studies have shown that mitochondrial morphology can modulate organelle function and greatly affect stem cell behavior, thus affecting tissue homeostasis. As such, we previously showed that the accumulation of...
4.
Chen T, Lin K, Yang S, Tseng C, Wang Y, Lin C, et al.
Front Cell Dev Biol . 2022 May; 10:877047. PMID: 35517512
Morphogen-mediated signaling is critical for proper organ development and stem cell function, and well-characterized mechanisms spatiotemporally limit the expression of ligands, receptors, and ligand-binding cell-surface glypicans. Here, we show that...
5.
Tseng T, Wang Y, Tsao C, Ke Y, Lee Y, Hsu H, et al.
Development . 2021 Jul; 148(15). PMID: 34323273
Vertebrate animals usually display robust growth trajectories during juvenile stages, and reversible suspension of this growth momentum by a single genetic determinant has not been reported. Here, we report a...
6.
Amartuvshin O, Lin C, Hsu S, Kao S, Chen A, Tang W, et al.
Aging Cell . 2020 Jul; 19(8):e13191. PMID: 32666649
Changes in mitochondrial dynamics (fusion and fission) are known to occur during stem cell differentiation; however, the role of this phenomenon in tissue aging remains unclear. Here, we report that...
7.
Lin K, Wang W, Lin C, Rastegari E, Su Y, Chang Y, et al.
Nat Commun . 2020 Jun; 11(1):3147. PMID: 32561720
Transposons are known to participate in tissue aging, but their effects on aged stem cells remain unclear. Here, we report that in the Drosophila ovarian germline stem cell (GSC) niche,...
8.
Lin K, Hsu H
Curr Opin Insect Sci . 2020 Feb; 37:16-22. PMID: 32070932
Insect oogenesis is greatly affected by nutrient availability. When nutrients are abundant, oocytes are rapidly generated, but the process is slowed to conserve energy under nutrient-deficient conditions. To properly allocate...
9.
Rastegari E, Kajal K, Tan B, Huang F, Chen R, Hsieh T, et al.
Development . 2020 Jan; 147(2). PMID: 31941704
WD40 proteins control many cellular processes via protein interactions. Wuho (Wh, a WD40 protein) controls fertility, although the involved mechanisms are unclear. Here, we show that Wh promotion of Mei-p26...
10.
Hsu H, Bahader M, Lai C
Cell Mol Life Sci . 2019 Jul; 76(21):4309-4317. PMID: 31300869
Adult stem cells have a unique capacity to renew themselves and generate differentiated cells that are needed in the body. These cells are recruited and maintained by the surrounding microenvironment,...