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Hussein Hamze

Explore the profile of Hussein Hamze including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Hamze H, Jaafar M, Khreiss A, Dominique C, Bourdeaux J, Santo P, et al.
Nucleic Acids Res . 2025 Mar; 53(5). PMID: 40037705
The early steps of large-ribosomal-subunit assembly feature among the least understood steps of ribosome synthesis in eukaryotes. In Saccharomyces cerevisiae, the box C/D chaperone small nucleolar ribonucleoprotein (snoRNP) snR190 and...
2.
Dominique C, Maiga N, Mendez-Godoy A, Pillet B, Hamze H, Leger-Silvestre I, et al.
Nat Commun . 2024 Nov; 15(1):9415. PMID: 39482307
Intrinsically disordered regions (IDRs) are highly enriched in the nucleolar proteome but their physiological role in ribosome assembly remains poorly understood. Our study reveals the functional plasticity of the extremely...
3.
Mitterer V, Hamze H, Kunowska N, Stelzl U, Henras A, Hurt E
Nucleic Acids Res . 2023 Dec; 52(4):1975-1987. PMID: 38113283
During ribosome biogenesis a plethora of assembly factors and essential enzymes drive the unidirectional maturation of nascent pre-ribosomal subunits. The DEAD-box RNA helicase Dbp10 is suggested to restructure pre-ribosomal rRNA...