Huizhou Fan
Overview
Explore the profile of Huizhou Fan including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
2409
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Recent Articles
1.
Wan D, Pan M, Zhong G, Fan H
Infect Immun
. 2025 Feb;
93(3):e0060224.
PMID: 39918305
The virulence plasmid of the obligate intracellular bacterium encodes eight proteins. Among these, Pgp3 is crucial for pathogenicity, and Pgp4 functions as a transcriptional regulator of both plasmid and chromosomal...
2.
Wan D, Pan M, Zhong G, Fan H
bioRxiv
. 2024 Nov;
PMID: 39569140
The virulence plasmid of the obligate intracellular bacterium encodes eight proteins. Among these, Pgp3 is crucial for pathogenicity, and Pgp4 functions as a transcriptional regulator of both plasmid and chromosomal...
3.
Wan D, Cheng A, Wang Y, Zhong G, Li W, Fan H
BMC Genomics
. 2024 Aug;
25(1):801.
PMID: 39182031
Background: RNA sequencing (RNA-Seq) offers profound insights into the complex transcriptomes of diverse biological systems. However, standard differential expression analysis pipelines based on DESeq2 and edgeR encounter challenges when applied...
4.
Wang Y, Fondell J, Zhong G, Fan H
Microbiol Spectr
. 2024 Jun;
12(8):e0013224.
PMID: 38916351
No abstract available.
5.
Wan D, Cheng A, Wang Y, Zhong G, Li W, Fan H
bioRxiv
. 2024 Jun;
PMID: 38826265
Motivation: RNA sequencing (RNA-Seq) offers profound insights into the complex transcriptomes of diverse biological systems. However, standard differential expression analysis pipelines based on DESeq2 and edgeR encounter challenges when applied...
6.
Wurihan W, Wang Y, Yeung S, Zou Y, Lai Z, Fondell J, et al.
Infect Immun
. 2024 Feb;
92(3):e0053923.
PMID: 38299827
The obligate intracellular bacterium has a unique developmental cycle that alternates between two contrasting cell types. With a hardy envelope and highly condensed genome, the small elementary body (EB) maintains...
7.
Lu B, Wang Y, Wurihan W, Cheng A, Yeung S, Fondell J, et al.
mBio
. 2023 Dec;
15(1):e0203623.
PMID: 38112466
Hallmarks of the developmental cycle of the obligate intracellular pathogenic bacterium are the primary differentiation of the infectious elementary body (EB) into the proliferative reticulate body (RB) and the secondary...
8.
Lu B, Wang Y, Wurihan W, Cheng A, Yeung S, Fondell J, et al.
bioRxiv
. 2023 Aug;
PMID: 37577610
, an obligate intracellular bacterial pathogen, has a unique developmental cycle involving the differentiation of invading elementary bodies (EBs) to noninfectious reticulate bodies (RBs), replication of RBs, and redifferentiation of...
9.
Lu B, Qiao Q, Park E, Wang Y, Gilleran J, Pan M, et al.
ACS Omega
. 2023 Feb;
8(7):6597-6607.
PMID: 36844602
Chlamydiae are obligate intracellular Gram-negative bacteria and widespread pathogens in humans and animals. Broad-spectrum antibiotics are currently used to treat chlamydial infections. However, broad-spectrum drugs also kill beneficial bacteria. Recently,...
10.
Cheng A, Wan D, Ghatak A, Wang C, Feng D, Fondell J, et al.
mBio
. 2023 Jan;
14(1):e0349922.
PMID: 36719197
Gene transcription in bacteria is carried out by the multisubunit RNA polymerase (RNAP), which is composed of a catalytic core enzyme and a promoter-recognizing σ factor. The core enzyme comprises...