Huizhi Zhao
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Explore the profile of Huizhi Zhao including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
507
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Recent Articles
1.
Gao C, Zhang H, Wang Y, Wang S, Guo X, Han Y, et al.
Cells
. 2024 Jul;
13(13.
PMID: 38995000
Erythropoiesis occurs first in the yolk sac as a transit "primitive" form, then is gradually replaced by the "definitive" form in the fetal liver (FL) during fetal development and in...
2.
Yang Q, Chen L, Zhang H, Li M, Sun L, Wu X, et al.
Cell Death Differ
. 2024 May;
31(8):999-1012.
PMID: 38719927
The dynamic balance of DNA methylation and demethylation is required for erythropoiesis. Our previous transcriptomic analyses revealed that DNA methyltransferase 1 (DNMT1) is abundantly expressed in erythroid cells at all...
3.
Han Y, Gao C, Liu Y, Zhang H, Wang S, Zhao H, et al.
Blood
. 2023 Dec;
143(11):1018-1031.
PMID: 38127913
Disordered erythropoiesis is a feature of many hematologic diseases, including sickle cell disease (SCD). However, very little is known about erythropoiesis in SCD. Here, we show that although bone marrow...
4.
Han Y, Wang S, Wang Y, Huang Y, Gao C, Guo X, et al.
Genomics Proteomics Bioinformatics
. 2023 Sep;
21(6):1117-1132.
PMID: 37657739
The fetal liver (FL) is the key erythropoietic organ during fetal development, but knowledge on human FL erythropoiesis is very limited. In this study, we sorted primary erythroblasts from FL...
5.
Li M, Liu D, Xue F, Zhang H, Yang Q, Sun L, et al.
Haematologica
. 2023 Apr;
108(9):2487-2502.
PMID: 37021526
Enhancer of zeste homolog 2 (EZH2) is the lysine methyltransferase of polycomb repressive complex 2 (PRC2) that catalyzes H3K27 tri-methylation. Aberrant expression and loss-of-function mutations of EZH2 have been demonstrated...
6.
Zhang H, Xue F, Zhao H, Chen L, Wang T, Wu X
Epigenomics
. 2022 Nov;
14(20):1249-1267.
PMID: 36420716
To investigate DNA methylation patterns in early and terminal stages of erythropoiesis, and to explore the function of differentially methylated genes in erythropoiesis and erythroid disorders. Differential analysis of DNA...
7.
Xu Y, Wang B, Zhang M, Zhang J, Li Y, Jia P, et al.
Adv Mater
. 2022 Mar;
34(19):e2200905.
PMID: 35294781
Due to the adverse effects of erythropoietin (EPO) on cancer patient survival, it is necessary to develop new agents that can be used to efficiently manage and treat cancer-related anemia....
8.
Wang S, Zhao H, Zhang H, Gao C, Guo X, Chen L, et al.
J Cell Mol Med
. 2022 Mar;
26(8):2404-2416.
PMID: 35249258
Red blood cells (RBCs) generated ex vivo have the potential to be used for transfusion. Human embryonic stem cells (ES) and induced pluripotent stem cells (iPS) possess unlimited self-renewal capacity...
9.
An C, Huang Y, Li M, Xue F, Nie D, Zhao H, et al.
Blood Adv
. 2021 Sep;
5(22):4648-4661.
PMID: 34551066
Enucleation is a key event in mammalian erythropoiesis responsible for the generation of enucleated reticulocytes. Although progress is being made in developing mechanistic understanding of enucleation, our understanding of mechanisms...
10.
Wang Y, Li W, Schulz V, Zhao H, Qu X, Qi Q, et al.
Blood
. 2021 May;
138(17):1615-1627.
PMID: 34036344
Histone deacetylases (HDACs) are a group of enzymes that catalyze the removal of acetyl groups from histone and nonhistone proteins. HDACs have been shown to have diverse functions in a...