Huikun Zhang
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Explore the profile of Huikun Zhang including associated specialties, affiliations and a list of published articles.
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21
Citations
226
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Recent Articles
11.
Xu Q, Shao Y, Zhang J, Zhang H, Zhao Y, Liu X, et al.
Cancer Res Treat
. 2019 Jul;
52(1):218-245.
PMID: 31291711
Purpose: Anterior gradient 3 (AGR3) belongs to human anterior gradient (AGR) family. The function of AGR3 on cancer remains unknown. This research aimed to investigate if AGR3 had prognostic values...
12.
Shao Y, Chong W, Liu X, Xu Y, Zhang H, Xu Q, et al.
Cell Death Dis
. 2019 Jun;
10(6):431.
PMID: 31160551
Intersectin1 (ITSN1) contains two isoforms: ITSN1-S and ITSN1-L, which is highly regulated by alternative splicing. However, the alteration of alternative splicing and its importance in cancer is still unknown. In...
13.
Qin F, Zhang H, Huang Y, Yang L, Yu F, Liu X, et al.
Oncotarget
. 2018 Jan;
8(67):112060-112075.
PMID: 29340111
Defining biomarkers that predict therapeutic effects and adverse events is a crucial mandate to guide patient selection for personalized cancer treatments. DPD (dihydropyrimidine dehydrogenase, encoded by gene) is the initial...
14.
Zhang H, Yu F, Qin F, Shao Y, Chong W, Guo Z, et al.
FASEB J
. 2017 Dec;
32(5):2395-2410.
PMID: 29259035
Girdin is an actin-binding protein playing key roles in the development of various carcinomas. Although online tools have predicted nuclear localization of girdin with a high probability, convincing proof has...
15.
Zhang H, Qin F, Yang L, He J, Liu X, Shao Y, et al.
Oncotarget
. 2017 Dec;
8(59):99414-99428.
PMID: 29245912
Previous research usually focused on single protein or gene in tumor development, actually highly heterogeneous nature and different signaling pathways largely contribute to tumor progression and tumor patients' outcomes. Therefore,...
16.
Ericksen S, Wu H, Zhang H, Michael L, Newton M, Hoffmann F, et al.
J Chem Inf Model
. 2017 Jun;
57(7):1579-1590.
PMID: 28654262
In structure-based virtual screening, compound ranking through a consensus of scores from a variety of docking programs or scoring functions, rather than ranking by scores from a single program, provides...
17.
Qin F, Zhang H, Shao Y, Liu X, Yang L, Huang Y, et al.
Oncotarget
. 2016 Jan;
7(7):8143-54.
PMID: 26812884
Aquaporin1 (AQP1) belongs to a highly conserved family of aquaporin proteins which facilitate water flux across cell membranes. Although emerging evidences indicated the cytoplasm was important for AQP1 localization, the...
18.
Dai K, Qin F, Zhang H, Liu X, Guo C, Zhang M, et al.
Oncotarget
. 2015 Dec;
7(4):4770-84.
PMID: 26684357
Bone morphogenetic protein receptor type IB (BMPRIB) is one osteogenesis factor, which function in breast cancer has been rarely explored until recently. In the clinical study presented here, involving a...
19.
Qin F, Zhang H, Ma L, Liu X, Dai K, Li W, et al.
Sci Rep
. 2015 Sep;
5:14430.
PMID: 26400100
Brain metastasis is a significant unmet clinical problem in breast cancer treatment. It is always associated with poor prognosis and high morbidity. Recently, Slit2/Robo1 pathway has been demonstrated to be...
20.
Gu F, Zhang H, Qin F, Liu X, Li W, Fu L, et al.
Glia
. 2015 Apr;
63(9):1595-605.
PMID: 25832561
Glioblastomas, the most aggressive form of primary brain tumors with a tendency to invade surrounding healthy brain tissues, remains an incurable disease. Intersectin (ITSN) is a multidomain adapter protein implicated...