Hui-Ru Shieh
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Explore the profile of Hui-Ru Shieh including associated specialties, affiliations and a list of published articles.
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23
Citations
245
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Recent Articles
1.
Chang W, Chen Y, Lin C, Wang C, Shieh H, Chi C, et al.
Biomedicines
. 2024 Jul;
12(7).
PMID: 39062140
Colon cancer has a poor clinical response to anti-PD1 therapy. This study aimed to evaluate the effect of cordycepin on the efficacy of anti-PD1 treatment in colon cancer. The viability...
2.
Chen Y, Yang Y, Shieh H, Lin Y, Ke W, Chiu C
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791440
The gene cluster for Type IV pilus (Tfp) biosynthesis is commonly present and highly conserved in . Nevertheless, Tfp-mediated twitching motility is less common among strains, and the factors determining...
3.
Kuo F, Lai J, Shieh H, Liou W, Bair M, Chen Y
Biomedicines
. 2024 Mar;
12(3).
PMID: 38540311
Histamine modulates immunity by binding to histamine receptor 2 (H2R). Cimetidine, an H2R antagonist that inhibits gastric acid secretion and treats gastrointestinal ulcers, interferes with histamine-mediated immunomodulation and may have...
4.
Midostaurin Modulates Tumor Microenvironment and Enhances Efficacy of Anti-PD-1 against Colon Cancer
Lai C, Chi C, Wu S, Shieh H, Yen J, Chen Y
Cancers (Basel)
. 2022 Oct;
14(19).
PMID: 36230769
Immunotherapy modulating the tumor microenvironment (TME) immune function has a promising effect on various types of cancers, but it remains as a limited efficacy in colon cancer. Midostaurin (PKC412) has...
5.
Geng J, Luo S, Shieh H, Wang H, Hu S, Chen Y
Int J Mol Sci
. 2022 Jul;
23(14).
PMID: 35887256
CodY is a dominant regulator in low G + C, Gram-positive Firmicutes that governs the regulation of various metabolic pathways and cellular processes. By using various bioinformatics analyses and DNA...
6.
Chen Y, Tsai P, Ye Z, Huang Y, Shieh H, Wu C, et al.
mSphere
. 2020 Oct;
5(5).
PMID: 33055259
is a dominant isolate of dental plaque and an opportunistic pathogen associated with subacute endocarditis. As the expression of collagen binding proteins (CBPs) could promote the establishment of in the...
7.
Liu S, Huang W, Yeh H, Ko C, Shieh H, Hung C, et al.
Cancers (Basel)
. 2019 Apr;
11(4).
PMID: 31022941
The combined administration of programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors might be considered as a treatment for poorly responsive cancer. We report a...
8.
Chen W, Chen C, Chi C, Li L, Lin C, Shieh H, et al.
J Clin Med
. 2019 Feb;
8(2).
PMID: 30764514
Esophageal cancer prognosis remains poor in current clinical practice. We previously reported that moscatilin can induce apoptosis and mitotic catastrophe in esophageal cancer cells, accompanied by upregulation of polo-like kinase...
9.
Lee M, Tseng W, Lai J, Shieh H, Chi C, Chen Y
Molecules
. 2018 Sep;
23(10).
PMID: 30248933
6-(methylsulfinyl) hexyl isothiocyanate (6-MITC) is a naturally occurring compound isolated from (wasabi). The synthetic derivatives, 6-(methylsulfenyl) hexyl isothiocyanate (I7447) and 6-(methylsulfonyl) hexyl isothiocyanate (I7557), were derived from 6-MITC with the...
10.
Chen S, Lee T, Tsai T, Huang Y, Lin Y, Lin C, et al.
Oncotarget
. 2017 Nov;
8(51):88563-88574.
PMID: 29179457
Purpose: The induction of autophagic cell death is an important process in the development of anticancer therapeutics. We aimed to evaluate the activity of the ancient Chinese decoction Danggui Buxue...