Hugo Roume
Overview
Explore the profile of Hugo Roume including associated specialties, affiliations and a list of published articles.
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35
Citations
2469
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Recent Articles
1.
Roume H, Mondot S, Saliou A, Le Fresne-Languille S, Dore J
Sci Rep
. 2023 Dec;
13(1):22593.
PMID: 38114587
Next-generation sequencing workflows, using either metabarcoding or metagenomic approaches, have massively contributed to expanding knowledge of the human gut microbiota, but methodological bias compromises reproducibility across studies. Where these biases...
2.
Fan Y, Stoving R, Berreira Ibraim S, Hyotylainen T, Thirion F, Arora T, et al.
Nat Microbiol
. 2023 Apr;
8(5):787-802.
PMID: 37069399
Anorexia nervosa (AN) is an eating disorder with a high mortality. About 95% of cases are women and it has a population prevalence of about 1%, but evidence-based treatment is...
3.
Meslier V, Quinquis B, Da Silva K, Plaza Onate F, Pons N, Roume H, et al.
Sci Data
. 2022 Nov;
9(1):694.
PMID: 36369227
Shotgun metagenomic sequencing is a common approach for studying the taxonomic diversity and metabolic potential of complex microbial communities. Current methods primarily use second generation short read sequencing, yet advances...
4.
Plaza Onate F, Roume H, Almeida M
Microbiol Resour Announc
. 2022 May;
11(6):e0025022.
PMID: 35532226
Here, we report the recovery of 89 metagenome-assembled genomes (MAGs) derived from a human fecal sample subjected to Pacific Biosciences (PacBio) high-fidelity (HiFi) sequencing. A total of 9 MAGs consisted...
5.
Ranaivo H, Thirion F, Bera-Maillet C, Guilly S, Simon C, Sothier M, et al.
Gut Microbes
. 2022 Mar;
14(1):2044722.
PMID: 35311446
Some cardiometabolic risk factors such as dyslipidemia and insulin resistance are known to be associated with low gut microbiota richness. A link between gut microbiota richness and the diversity of...
6.
Fromentin S, Forslund S, Chechi K, Aron-Wisnewsky J, Chakaroun R, Nielsen T, et al.
Nat Med
. 2022 Feb;
28(2):303-314.
PMID: 35177860
Previous microbiome and metabolome analyses exploring non-communicable diseases have paid scant attention to major confounders of study outcomes, such as common, pre-morbid and co-morbid conditions, or polypharmacy. Here, in the...
7.
Da Silva K, Guilly S, Thirion F, Le Chatelier E, Pons N, Roume H, et al.
BMC Microbiol
. 2022 Feb;
22(1):54.
PMID: 35151268
Background: Diosmectite, a natural colloidal clay, has been used worldwide for a number of approved indications, including the treatment of chronic functional diarrhea. Here, we used high-resolution whole metagenome shotgun...
8.
Derosa L, Routy B, Thomas A, Iebba V, Zalcman G, Friard S, et al.
Nat Med
. 2022 Feb;
28(2):315-324.
PMID: 35115705
Aside from PD-L1 expression, biomarkers of response to immune checkpoint inhibitors (ICIs) in non-small-cell lung cancer (NSCLC) are needed. In a previous retrospective analysis, we documented that fecal Akkermansia muciniphila...
9.
Belda E, Voland L, Tremaroli V, Falony G, Adriouch S, Assmann K, et al.
Gut
. 2022 Jan;
71(12):2463-2480.
PMID: 35017197
Objectives: Gut microbiota is a key component in obesity and type 2 diabetes, yet mechanisms and metabolites central to this interaction remain unclear. We examined the human gut microbiome's functional...
10.
Forslund S, Chakaroun R, Zimmermann-Kogadeeva M, Marko L, Aron-Wisnewsky J, Nielsen T, et al.
Nature
. 2021 Dec;
600(7889):500-505.
PMID: 34880489
During the transition from a healthy state to cardiometabolic disease, patients become heavily medicated, which leads to an increasingly aberrant gut microbiome and serum metabolome, and complicates biomarker discovery. Here,...