Hugo Osorio
Overview
Explore the profile of Hugo Osorio including associated specialties, affiliations and a list of published articles.
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Articles
95
Citations
1977
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Recent Articles
1.
Valentim-Coelho C, Saraiva J, Osorio H, Antunes M, Vaz F, Neves S, et al.
Biochim Biophys Acta Mol Basis Dis
. 2025 Mar;
1871(5):167767.
PMID: 40043591
Obstructive Sleep Apnea (OSA) is characterized by recurrent-episodes of apneas/hypopneas during sleep, leading to recurrent intermittent-hypoxia and sleep fragmentation. Non-treated OSA can result in cardiometabolic diseases. In this study, we...
2.
Silva C, Casanova M, Ferreirinha P, da Silva Morais A, Osorio H, Lima A, et al.
Life Sci
. 2025 Jan;
362():123366.
PMID: 39761741
Aims: The development and selection of T cells occur within the thymus. This organ involutes throughout life, compromising the generation of T cells and, consequently, the efficacy of the immune...
3.
Girao H, Macario-Monteiro J, Figueiredo A, Silva E Sousa R, Doria E, Demidov V, et al.
Nat Commun
. 2024 Nov;
15(1):9720.
PMID: 39521805
Post-translational cycles of α-tubulin detyrosination and tyrosination generate microtubule diversity, the cellular functions of which remain largely unknown. Here we show that α-tubulin detyrosination regulates kinetochore-microtubule attachments to ensure normal...
4.
Goncalves B, Pires D, Fernandes L, Pacheco M, Ferreira T, Osorio H, et al.
Microbiol Spectr
. 2024 Nov;
:e0120124.
PMID: 39494883
The vaginal acidic environment potentiates the formation of biofilms, leading to complicated and recurrent infections. Importantly, the production of matrix is known to contribute to the recalcitrant features of biofilms....
5.
Mosquito management strategies in European rice fields: Environmental and public health perspectives
Gonzalez M, Chaskopoulou A, Georgiou L, Frontera E, Caceres F, Masia M, et al.
J Environ Manage
. 2024 Sep;
370:122534.
PMID: 39316873
Rice is a crucial food source and an important economic activity globally. Rice fields provide habitats for birds and other organisms but also serve as ideal breeding grounds for mosquitoes,...
6.
Chagas A, Ribeiro D, Osorio H, Abreu A, Okino C, Niciura S, et al.
Vet Parasitol
. 2024 Aug;
331:110280.
PMID: 39116550
Due to the negative impact of Haemonchus contortus in the tropics and subtropics, the detection of serum protein profiles that occur in infected sheep is of high relevance for targeted...
7.
Almeida-Nunes D, Nunes M, Osorio H, Ferreira V, Lobo C, Monteiro P, et al.
Biochem Biophys Rep
. 2024 Jul;
39:101755.
PMID: 38974022
Ovarian cancer (OC) patients develop ascites, an accumulation of ascitic fluid in the peritoneal cavity anda sign of tumour dissemination within the peritoneal cavity. This body fluid is under-researched, mainly...
8.
Nanoparticles targeting Sialyl-Tn for efficient tyrosine kinase inhibitor delivery in gastric cancer
Diniz F, Lamas S, Osorio H, Aguiar P, Freitas D, Gartner F, et al.
Acta Biomater
. 2023 Aug;
170:142-154.
PMID: 37586448
Gastric cancer (GC) is the fourth leading cause of cancer-related deaths worldwide and, therefore, it is urgent to develop new and more efficient therapeutic approaches. Foretinib (FRT) is an oral...
9.
Peixoto J, Principe C, Pestana A, Osorio H, Pinto M, Prazeres H, et al.
Int J Mol Sci
. 2023 Jul;
24(14).
PMID: 37511044
remains one of the most altered genes in cancer, although its relevance in cancer biology is still unclear. Recent advances in gene editing techniques, particularly CRISPR/Cas9 systems, offer new opportunities...
10.
Sao Jose C, Pereira C, Ferreira M, Andre A, Osorio H, Gullo I, et al.
Biology (Basel)
. 2023 Jun;
12(6).
PMID: 37372088
Cadherins are cell-cell adhesion molecules, fundamental for cell architecture and polarity. E-cadherin to P-cadherin switch can rescue adherens junctions in epithelial tumours. Herein, we disclose a mechanism for E-cadherin to...