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Hugo Gagnon

Explore the profile of Hugo Gagnon including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 242
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Recent Articles
1.
Gagnon H, Nguyen C, Hatami A, Begin P, Grzywacz K
Pediatr Allergy Immunol . 2024 Aug; 35(8):e14217. PMID: 39109472
No abstract available.
2.
Shajari E, Gagne D, Malick M, Roy P, Noel J, Gagnon H, et al.
Biomedicines . 2024 Feb; 12(2). PMID: 38397935
Inflammatory bowel disease (IBD) flare-ups exhibit symptoms that are similar to other diseases and conditions, making diagnosis and treatment complicated. Currently, the gold standard for diagnosing and monitoring IBD is...
3.
Nickerson J, Gagnon H, Wentzell P, Doucette A
Proteomics . 2024 Feb; 24(10):e2300339. PMID: 38299459
Detergent-based workflows incorporating sodium dodecyl sulfate (SDS) necessitate additional steps for detergent removal ahead of mass spectrometry (MS). These steps may lead to variable protein recovery, inconsistent enzyme digestion efficiency,...
4.
Gagnon H, Duguay S, Prasil P, Castilloux J
J Pediatr Gastroenterol Nutr . 2023 Jul; 77(5):592-596. PMID: 37496148
Introduction: Given the lack of data to help caregivers in the follow-up of Hirschsprung disease (HD), this study aimed to compare the functional outcomes of isolated Hirschsprung disease (I-HD) to...
5.
Gagne D, Shajari E, Thibault M, Noel J, Boisvert F, Babakissa C, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36232903
Necrotizing enterocolitis (NEC) is a life-threatening condition for premature infants in neonatal intensive care units. Finding indicators that can predict NEC development before symptoms appear would provide more time to...
6.
Lewandowska-Goch M, Kwiatkowska A, Lepek T, Ly K, Navals P, Gagnon H, et al.
ACS Med Chem Lett . 2021 Mar; 12(3):365-372. PMID: 33738063
Furin plays an important role in various pathological states, especially in bacterial and viral infections. A detailed understanding of the structural requirements for inhibitors targeting this enzyme is crucial to...
7.
Vincent L, Lapointe C, Lo M, Gagnon H, Pejler G, Takai S, et al.
J Pharmacol Exp Ther . 2020 Nov; 376(2):213-221. PMID: 33154104
Mouse mast cell protease 4 (mMCP-4), the murine functional analog to the human chymase, is a serine protease synthesized and stored in mast cell secretory granules. Our previous studies reported...
8.
Ahuie G, Gagnon H, Pace P, Peskin A, Wagner R, Naylor S, et al.
Rapid Commun Mass Spectrom . 2020 Mar; 34(11):e8774. PMID: 32119756
Rationale: Oxidative stress is an imbalance between reactive free radical oxygen species and antioxidant defenses. Its consequences can lead to numerous pathologies. Regulating oxidative stress is the complex interplay between...
9.
Ahuie Kouakou G, Gagnon H, Lacasse V, Wagner J, Naylor S, Klarskov K
Free Radic Biol Med . 2019 Jun; 141:233-243. PMID: 31228548
Ascorbic acid (vitamin C) plays a significant role in the prevention of oxidative stress. In this process, ascorbate is oxidized to dehydroascorbate (DHA). We have investigated the impact of DHA...
10.
Houde M, Schwertani A, Touil H, Desbiens L, Sarrhini O, Lecomte R, et al.
Front Pharmacol . 2018 Sep; 9:868. PMID: 30233357
Chymase, a mast cell serine protease involved in the generation of multiple cardiovascular factors, such as angiotensin II and endothelin-1 (ET-1), is elevated and participates in tissue degeneration after permanent...