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Hugo F Miranda

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Citations 217
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Recent Articles
1.
Miranda H, Noriega V, Sierralta F, Sotomayor-Zarate R, Prieto J
Fundam Clin Pharmacol . 2022 Jan; 36(3):494-500. PMID: 34989439
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the best therapeutic options to treat pain. Their use in combination with other drugs may broaden their applicability in analgesia if their ceiling and...
2.
Miranda H, Noriega V, Sierralta F, Sotomayor-Zarate R, Prieto J
Drug Res (Stuttg) . 2020 Jul; 70(9):424-428. PMID: 32707591
Pain models are mostly in rodents and between them formalin orofacial test allow discrimination among antinociception and anti-inflammation. This assay use a formalin solution injected into the upper right lip...
3.
Noriega V, Miranda H, Prieto J, Sotomayor-Zarate R, Sierralta F
Drug Res (Stuttg) . 2020 Jan; 70(4):145-150. PMID: 32000276
There are different animal models to evaluate pain among them the formalin hind paw assay which is widely used since some of its events appear to be similar to the...
4.
Miranda H, Noriega V, Sierralta F, Poblete P, Aranda N, Prieto J
Drug Res (Stuttg) . 2019 Aug; 69(12):688-694. PMID: 31408903
Different NSAIDs are used as antinociceptive in various analgesic assays, among which should be mentioned: ibuprofen, ketorolac , ketoprofen, meloxicam , paracetamol and others. It has been shown that NSAIDs...
5.
Miranda H, Noriega V, Sierralta F, Poblete P, Aranda N, Prieto J
Drug Res (Stuttg) . 2019 Jun; 69(10):572-578. PMID: 31252435
The principal mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs) is the inhibition of ciclooxigenases. In this study was evaluated if NSAIDs could induce antinociceptive differences according to the type...
6.
Arrau S, Rodriguez-Diaz M, Cassels B, Valenzuela-Barra G, Delporte C, Barriga A, et al.
Curr Top Med Chem . 2019 May; 19(11):927-930. PMID: 31072292
Background: Quillaja saponaria Mol. bark contains a high concentration of triterpene saponins that have been used for centuries as a cleansing, antiinflammatory and analgesic agent in Chilean folk medicine. In...
7.
Vargas C, Miranda H, Sierralta F, Noriega V, Prieto J
Drug Dev Res . 2019 Feb; 80(4):471-474. PMID: 30767248
Nonsteroidal anti-inflammatory drugs (NSAIDs) possess as primary action mechanism the inhibition of cyclooxygenases (COX-1, COX-2, and COX-3), thus producing a decreasing prostaglandin synthesis. This study was designed to evaluate whether...
8.
Miranda H, Sierralta F, Aranda N, Poblete P, Noriega V, Prieto J
Fundam Clin Pharmacol . 2018 Aug; 32(6):581-588. PMID: 30069908
Neuropathic pain is associated with several conditions such as surgery, cancer, and diabetes and can be induced experimentally. Among the drugs used as monotherapy are gabapentin and tramadol. The purpose...
9.
Miranda H, Sierralta F, Aranda N, Poblete P, Castillo R, Noriega V, et al.
Pharmacol Rep . 2018 Apr; 70(3):503-508. PMID: 29660653
Background: Neuropathic pain, and subsequent hypernociception, can be induced in mice by paclitaxel (PTX) administration and partial sciatic nerve ligation (PSNL). Its pharmacotherapy has been a clinical challenge, due to...
10.
Miranda H, Sierralta F, Aranda N, Noriega V, Prieto J
Pharmacol Rep . 2018 Jan; 70(1):47. PMID: 29329029
No abstract available.