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Hugo F M C Martiniano

Explore the profile of Hugo F M C Martiniano including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Asif M, Martiniano H, Lamurias A, Kausar S, Couto F
BMC Bioinformatics . 2023 Apr; 24(1):171. PMID: 37101154
Background: Complex diseases such as neurodevelopmental disorders (NDDs) exhibit multiple etiologies. The multi-etiological nature of complex-diseases emerges from distinct but functionally similar group of genes. Different diseases sharing genes of...
2.
Asif M, Martiniano H, Marques A, Santos J, Vilela J, Rasga C, et al.
Transl Psychiatry . 2020 Feb; 10(1):43. PMID: 32066720
The complex genetic architecture of Autism Spectrum Disorder (ASD) and its heterogeneous phenotype makes molecular diagnosis and patient prognosis challenging tasks. To establish more precise genotype-phenotype correlations in ASD, we...
3.
Estacio S, Martiniano H, Faisca P
Mol Biosyst . 2016 Jun; 12(9):2834-48. PMID: 27354240
We employed high-temperature classical molecular dynamics (MD) simulations to investigate the unfolding process of the wild-type (WT) and F508del-NBD1 domains of CFTR protein, with and without second-site mutations. To rationalize...
4.
Martiniano H, Galamba N, Cabral B
J Chem Phys . 2014 May; 140(16):164511. PMID: 24784291
The electronic absorption spectrum of liquid water was investigated by coupling a one-body energy decomposition scheme to configurations generated by classical and Born-Oppenheimer Molecular Dynamics (BOMD). A Frenkel exciton Hamiltonian...