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Hugo C Castro-Faria-Neto

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Recent Articles
11.
Leardini-Tristao M, Andrade G, Garcia C, Reis P, Lourenco M, Moreira E, et al.
J Neuroinflammation . 2020 Apr; 17(1):117. PMID: 32299450
Background: Brain circulation disorders such as chronic cerebral hypoperfusion have been associated with a decline in cognitive function during the development of dementia. Astrocytes together with microglia participate in the...
12.
Silva A, Amorim E, Barbosa-Silva M, Lima M, Oliveira H, Granja M, et al.
Crit Care Med . 2020 Mar; 48(4):e290-e298. PMID: 32205619
Objectives: Survivors of sepsis are frequently left with significant cognitive and behavioral impairments. These complications derive from nonresolving inflammation that persists following hospital discharge. To date, no study has investigated...
13.
de Azevedo-Quintanilha I, Vieira-de-Abreu A, Ferreira A, Reis P, Silva T, Nascimento D, et al.
PLoS One . 2019 Dec; 14(12):e0224610. PMID: 31869339
Malaria is an infectious disease of major worldwide clinical importance that causes a variety of severe, or complicated, syndromes including cerebral malaria, which is often fatal. Leukocyte integrins are essential...
14.
Comim C, Ventura L, Freiberger V, Dias P, Bragagnolo D, Dutra M, et al.
Mol Neurobiol . 2019 May; 56(11):7608-7616. PMID: 31077034
Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that affects muscles and also the brain, resulting in memory and behavioral problems. In the pathogenesis of DMD, inflammation is an important...
15.
Freitas F, Estato V, Reis P, Castro-Faria-Neto H, Carvalho V, Torres R, et al.
Microcirculation . 2017 Sep; 24(8). PMID: 28865157
Objective: We investigated the acute effects of SIM on cerebral microvascular rarefaction and dysfunction in SHRs. Methods: Male WKY and SHRs were divided into 4 groups of 8 animals each:...
16.
Almeida F, Saraiva-Romanholo B, Vieira R, Takachi Moriya H, Ligeiro-de-Oliveira A, Lopes F, et al.
PLoS One . 2017 Jul; 12(7):e0181819. PMID: 28750097
Lung volume reduction surgery (LVRS) is an option for emphysematous patients who are awaiting lung transplantation. LVRS reduces nonfunctional portions of lung tissues and favors the compensatory lung growth (CLG)...
17.
Assuncao L, Magalhaes K, Carneiro A, Molinaro R, Almeida P, Atella G, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2016 Nov; 1862(2):246-254. PMID: 27871882
Mansonic schistosomiasis is a disease caused by the trematode Schistosoma mansoni, endemic to tropical countries. S. mansoni infection induces the formation of granulomas and potent polarization of Th2-type immune response....
18.
Reis P, Alexandre P, dAvila J, Siqueira L, Antunes B, Estato V, et al.
Brain Behav Immun . 2016 Nov; 60:293-303. PMID: 27833044
Acute brain dysfunction is a frequent condition in sepsis patients and is associated with increased mortality and long-term neurocognitive consequences. Impaired memory and executive function are common findings in sepsis...
19.
Lakshmikanth C, Jacob S, Kudva A, Latchoumycandane C, Yashaswini P, Sumanth M, et al.
Sci Rep . 2016 Oct; 6:34666. PMID: 27698491
The endotoxin lipopolysaccharide (LPS) promotes sepsis, but bacterial peptides also promote inflammation leading to sepsis. We found, intraperitoneal administration of live or heat inactivated E. coli JE5505 lacking the abundant...
20.
de Azevedo-Quintanilha I, Vieira-de-Abreu A, Ferreira A, Nascimento D, Siqueira A, Campbell R, et al.
Malar J . 2016 Jul; 15(1):393. PMID: 27473068
Background: Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a potentially lethal complication of clinical malaria. Acute lung injury in MA-ARDS shares features with ARDS triggered by other causes, including alveolar...