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Hugo A Penny

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Articles 29
Citations 182
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Recent Articles
1.
Raju S, Ingham K, Green O, Johnson C, Shiha M, Nandi N, et al.
J Gastrointestin Liver Dis . 2024 Dec; 33(4):482-487. PMID: 39733322
Background And Aims: In coeliac disease, the clinical role of the urinary gluten immunogenic peptide is unclear. It has been suggested it can be a non-invasive marker of villous atrophy....
2.
Shiha M, Hadjisavvas N, Sanders D, Penny H
Br J Hosp Med (Lond) . 2024 Sep; 85(9):1-21. PMID: 39347683
Coeliac disease is a common autoimmune disorder that affects nearly 1% of the general population. Current diagnostic strategies involve active case finding, serological tests, and endoscopy with biopsies. However, many...
3.
Shiha M, Wickramasekera N, Raju S, Penny H, Sanders D
United European Gastroenterol J . 2024 Aug; PMID: 39192618
Background: There is potential for a paradigm shift from a biopsy-to a serology-based diagnosis of coeliac disease in selected adult patients. However, it remains unknown if this approach would be...
4.
Shiha M, Schiepatti A, Maimaris S, Nandi N, Penny H, Sanders D
Gut . 2024 Aug; 73(12):1944-1952. PMID: 39153845
Objective: Potential coeliac disease (PCD) is characterised by positive serological and genetic markers of coeliac disease with architecturally preserved duodenal mucosa. The clinical outcomes and rates of progression to overt...
5.
Shiha M, Oka P, Nandi N, Ingham K, Raju S, Penny H, et al.
Dig Liver Dis . 2024 Aug; 57(1):206-212. PMID: 39095248
Background: Small bowel capsule endoscopy (CE) and double-balloon enteroscopy (DBE) are recommended for the management of patients with nonresponsive or refractory coeliac disease (CD). However, there is a paucity of...
6.
Raju S, Shiha M, Penny H
Curr Opin Gastroenterol . 2024 Mar; 40(3):190-195. PMID: 38547329
Purpose Of Review: Persistent villous atrophy is associated with morbidity in coeliac disease and most commonly due to ongoing gluten ingestion. Current methods for assessing gluten exposure and persisting villous...
7.
Raju S, Greenaway E, Schiepatti A, Arpa G, Vecchione N, Jian C, et al.
Gut . 2024 Mar; 73(7):1124-1130. PMID: 38499339
Background: Ultra-short coeliac disease (USCD) is defined as villous atrophy only present in the duodenal bulb (D1) with concurrent positive coeliac serology. We present the first, multicentre, international study of...
8.
Shiha M, Nandi N, Hutchinson A, Raju S, Tai F, Elli L, et al.
Frontline Gastroenterol . 2024 Feb; 15(2):95-98. PMID: 38420132
Objective: Recent evidence suggests that adult patients with IgA tissue transglutaminase levels of ≥10× the upper limit of normal could be accurately diagnosed with coeliac disease without undergoing endoscopy and...
9.
Penny H, Aziz I, Lam C
Curr Opin Gastroenterol . 2024 Feb; 40(3):225-232. PMID: 38393310
Purpose Of Review: Individuals with joint hypermobility disorders are increasingly referred to gastroenterology services for support with the investigation and management of gastrointestinal complaints. Individuals can present with a myriad...
10.
Shiha M, Nandi N, Raju S, Wild G, Cross S, Singh P, et al.
Gastroenterology . 2024 Jan; 166(4):620-630. PMID: 38176661
Background & Aims: Current international guidelines recommend duodenal biopsies to confirm the diagnosis of celiac disease in adult patients. However, growing evidence suggests that immunoglobulin A (IgA) anti-tissue transglutaminase (tTg)...