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Hugh M D Gurling

Explore the profile of Hugh M D Gurling including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 981
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Recent Articles
1.
Fiorentino A, Sharp S, Kandaswamy R, Gurling H, Bass N, McQuillin A
Psychiatr Genet . 2016 Feb; 26(2):99-100. PMID: 26901794
No abstract available.
2.
Duan J, Shi J, Fiorentino A, Leites C, Chen X, Moy W, et al.
Am J Hum Genet . 2014 Dec; 95(6):744-53. PMID: 25434007
Schizophrenia (SZ) genome-wide association studies (GWASs) have identified common risk variants in >100 susceptibility loci; however, the contribution of rare variants at these loci remains largely unexplored. One of the...
3.
Sharp S, McQuillin A, Marks M, Hunt S, Stanford S, Lydall G, et al.
Am J Med Genet B Neuropsychiatr Genet . 2014 May; 165B(4):373-80. PMID: 24817687
Single nucleotide polymorphisms (SNPs) in the tachykinin receptor 1 gene (TACR1) are nominally associated with bipolar affective disorder (BPAD) in a genome-wide association study and in several case-control samples of...
4.
Way M, McQuillin A, Saini J, Ruparelia K, Lydall G, Guerrini I, et al.
Addict Biol . 2014 Apr; 20(3):594-604. PMID: 24735490
Certain single nucleotide polymorphisms (SNPs) in genes encoding alcohol dehydrogenase (ADH) enzymes confer a significant protective effect against alcohol dependence syndrome (ADS) in East Asian populations. Recently, attention has focused...
5.
Quadri G, McQuillin A, Guerrini I, Thomson A, Cherian R, Saini J, et al.
Psychiatr Genet . 2014 Mar; 24(3):122-3. PMID: 24667528
No abstract available.
6.
Xu W, Cohen-Woods S, Chen Q, Noor A, Knight J, Hosang G, et al.
BMC Med Genet . 2014 Jan; 15:2. PMID: 24387768
Background: Recently, genome-wide association studies (GWAS) for cases versus controls using single nucleotide polymorphism microarray data have shown promising findings for complex neuropsychiatric disorders, including bipolar disorder (BD). Methods: Here...
7.
Anstee Q, Knapp S, Maguire E, Hosie A, Thomas P, Mortensen M, et al.
Nat Commun . 2013 Nov; 4:2816. PMID: 24281383
Alcohol dependence is a common, complex and debilitating disorder with genetic and environmental influences. Here we show that alcohol consumption increases following mutations to the γ-aminobutyric acidA receptor (GABAAR) β1...
8.
Sharp S, Hu Y, Weymer J, Rizig M, McQuillin A, Hunt S, et al.
Psychiatr Genet . 2013 Jul; 23(4):153-62. PMID: 23811784
Objectives: Clathrin-mediated endocytosis (CME) is an intracellular trafficking mechanism for packaging cargo, including G protein-coupled receptors (GPCRs), into clathrin-coated vesicles (CCVs). The antipsychotic chlorpromazine inhibits CCV assembly of adaptor protein...
9.
Kandaswamy R, McQuillin A, Sharp S, Fiorentino A, Anjorin A, Blizard R, et al.
JAMA Psychiatry . 2013 Apr; 70(6):591-8. PMID: 23575746
Importance: Genetic markers at the gene encoding the metabotropic glutamate receptor 3 (GRM3) showed allelic association with bipolar disorder. Objective: To screen the GRM3 gene and adjacent control regions of...
10.
Szyszka P, Sharp S, Dedman A, Gurling H, McQuillin A
Psychiatr Genet . 2011 Aug; 22(3):150-1. PMID: 21862950
No abstract available.