Hugh C Hemmings Jr
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Explore the profile of Hugh C Hemmings Jr including associated specialties, affiliations and a list of published articles.
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82
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Recent Articles
1.
Hollingworth D, Herold K, Kelly G, Mykhaylyk V, Xiang J, Zhang D, et al.
bioRxiv
. 2024 Nov;
PMID: 39574657
Volatile general anesthetics are used for inhalational anesthesia in hundreds of millions of surgical procedures annually, yet their mechanisms of action remain unclear. Membrane proteins involved in cell signaling are...
2.
Zhao Y, Ou M, Liu J, Jiang J, Zhang D, Ke B, et al.
J Neurosci
. 2024 Jun;
44(34).
PMID: 38926088
Current anesthetic theory is mostly based on neurons and/or neuronal circuits. A role for astrocytes also has been shown in promoting recovery from volatile anesthesia, while the exact modulatory mechanism...
3.
Eastman R, Rusinova R, Herold K, Huang X, Dranchak P, Voss T, et al.
bioRxiv
. 2023 Nov;
PMID: 37961094
Since it was proposed as a potential host-directed antiviral agent for SARS-CoV-2, the antiparasitic drug ivermectin has been investigated thoroughly in clinical trials, which have provided insufficient support for its...
4.
Speigel I, Patel K, Osman V, Hemmings Jr H
Neuropharmacology
. 2023 Sep;
240:109705.
PMID: 37683886
Volatile anesthetics alter presynaptic function through effects on Ca influx and neurotransmitter release. These actions are proposed to play important roles in their pleiotropic neurophysiological effects including immobility, unconsciousness and...
5.
Osman V, Speigel I, Patel K, Hemmings Jr H
eNeuro
. 2023 Aug;
10(8).
PMID: 37591734
Volatile anesthetics reduce excitatory synaptic transmission by both presynaptic and postsynaptic mechanisms which include inhibition of depolarization-evoked increases in presynaptic Ca concentration and blockade of postsynaptic excitatory glutamate receptors. The...
6.
Kaur G, Pryor K, Milewski A, Weinberg R, Hemmings Jr H
Br J Anaesth
. 2023 Jun;
131(2):e41-e43.
PMID: 37268447
No abstract available.
7.
Fitch W, Smith G, Hunter J, Reilly C, Mahajan R, Hemmings Jr H
Br J Anaesth
. 2023 Jan;
130(4):495.
PMID: 36702652
No abstract available.
8.
Hemmings Jr H, Lambert D
Br J Anaesth
. 2022 Dec;
130(1):1-2.
PMID: 36586729
In 2023, the British Journal of Anaesthesia commemorates its first century of publishing innovations in anaesthesia, pain, critical care and perioperative medicine. In honour of this special anniversary we outline...
9.
Fitch W, Smith G, Hunter J, Reilly C, Mahajan R, Hemmings Jr H
Br J Anaesth
. 2022 Nov;
130(1):3-7.
PMID: 36376100
At this centenary of the British Journal of Anaesthesia (BJA) in 2023, six of its 12 editors/editors-in-chief detail developments over the decades that have led to the BJA becoming a...
10.
Williams R, Johnson K, Lee F, Hemmings Jr H, Platholi J
Front Mol Neurosci
. 2022 Jul;
15:927149.
PMID: 35813074
Multiple presynaptic and postsynaptic targets have been identified for the reversible neurophysiological effects of general anesthetics on synaptic transmission and neuronal excitability. However, the synaptic mechanisms involved in persistent depression...