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Huda A Al Doghaither

Explore the profile of Huda A Al Doghaither including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 66
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Recent Articles
1.
Elmorsy E, Al Doghaither H, Al-Ghafari A, Amer S, Fawzy M, Toraih E
Reprod Toxicol . 2025 Feb; 132:108855. PMID: 39947444
Mercury (Hg) is known to be a hazardous toxin with a significant negative impact on female reproduction through mechanisms that remain unclear. The carotenoid fucoxanthin (FX) is an antioxidant with...
2.
Elmorsy E, Al-Ghafari A, Al Doghaither H
Curr Med Chem . 2025 Jan; PMID: 39819539
Background: Resveratrol (RES) is a phytochemical bioactive compound with suggested therapeutic benefits. Objective: The current work aimed to evaluate the anti-inflammatory effect of RES against palmitate (PA) induced lipotoxicity in...
3.
Elmorsy E, Al-Ghafari A, Al Doghaither H
Toxicol Res (Camb) . 2024 Dec; 13(6):tfae218. PMID: 39712643
Objective: Cadmium (Cd) and lead (Pb) are non-biodegradable heavy metals (HMs) that persistently contaminate ecosystems and accumulate in bones, where they exert harmful effects. This study aimed to investigate the...
4.
Elmorsy E, Al-Ghafari A, Al Doghaither H, Fawzy M, Shehata S
Steroids . 2024 Sep; 212:109514. PMID: 39303897
Despite the known therapeutic uses of dexamethasone (DEX), the specific mechanisms underlying its neurotoxic effects in neuronal cells, particularly in undifferentiated human neuroblastoma (SH-SY5Y) cells, remain inadequately understood. This study...
5.
Alenazi B, Al Doghaither H, Al-Ghafari A, Elmorsy E
Toxicol In Vitro . 2024 Sep; 101:105936. PMID: 39237056
Risperidone (RIS) is a widely used antipsychotic drug with reported alteration in immune response. The current study investigated mitochondrial disruption as the underlying mechanism of RIS-induced immunotoxicity in isolated human...
6.
Elmorsy E, Al-Ghafari A, Al Doghaither H, Alrowaili M, Khired Z, Toraih E, et al.
Biol Trace Elem Res . 2024 Sep; PMID: 39235540
Cadmium (Cd) and lead (Pb) are heavy metals (HMs) that persistently contaminate the ecosystem, and bioaccumulation in bones is a health concern. We used biochemical and molecular assays to assess...
7.
Elmorsy E, Al Doghaither H, Al-Ghafari A
J Biochem Mol Toxicol . 2024 Aug; 38(9):e23777. PMID: 39165170
Tramadol (TR), a commonly prescribed pain reliever for moderate to severe pain, has been associated with kidney damage. This study investigates TR-induced nephrotoxicity mechanisms, focusing on its effects on renal...
8.
Alkhattabi N, Khalifa F, Al Doghaither H, Al-Ghafari A, Tarbiah N, Sabban A
Int J Health Sci (Qassim) . 2024 Mar; 18(2):17-24. PMID: 38455596
Objective: The present study was designed to investigate the nephroprotective and immunoprotective effects of S-adenosyl-L-methionine (SAMe) in comparison to N-acetylcysteine (NAC) against ochratoxin A (OTA) - intoxication. Methods: Forty-eight adult...
9.
Arrait E, Al-Ghafari A, Al Doghaither H
Curr Oncol . 2023 Sep; 30(9):8039-8053. PMID: 37754498
We assess the contributions of genetic variants for the enzymes involved in capecitabine metabolism to colorectal cancer (CRC) development risk. In this case-control study, DNA samples were collected from 66...
10.
Alzahrani S, Al Doghaither H, Al-Ghafari A, Pushparaj P
Oncol Rep . 2023 Aug; 50(4). PMID: 37594133
Although 5‑fluorouracil (5‑FU)‑based chemotherapy is the major treatment for colorectal cancer, it has disadvantages such as systemic toxicity, lack of effectiveness and selectivity, and development of resistance. Capecitabine, a prodrug...