Huazhong Xie
Overview
Explore the profile of Huazhong Xie including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
45
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0
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Recent Articles
1.
Sun C, Chen Y, Gu Q, Fu Y, Wang Y, Liu C, et al.
Autophagy
. 2023 Dec;
20(3):645-658.
PMID: 38146933
ATG4B is a core protein and essential for cleaving precursor MAP1LC3/LC3 or deconjugating lipidated LC3-II to drive the formation of autophagosomes. The protein stability and activity of ATG4B regulated by...
2.
Xie H, Qiang P, Wang Y, Xia F, Liu P, Li M
Cell Biosci
. 2022 Dec;
12(1):206.
PMID: 36539845
Cysteine protease ATG4B, a key autophagy protein, is an attractive target for colorectal cancer therapy. However, ATG4B inhibitors with higher efficiency, safety, and clear mechanism are still limited. In this...
3.
Xia F, Fu Y, Xie H, Chen Y, Fang D, Zhang W, et al.
Redox Biol
. 2022 Mar;
52:102284.
PMID: 35349929
Autophagy is an evolutionarily conserved self-protecting mechanism implicated in cellular homeostasis. ATG4B plays a vital role in autophagy process via undertaking priming and delipidation of LC3. Chemical inhibitors and regulative...
4.
Zhao M, Xie H, Shan H, Zheng Z, Li G, Li M, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163026
Non-alcoholic fatty liver disease (NAFLD) is the fastest-growing liver disease in the world. Despite targeted agents which are needed to provide permanent benefits for patients with NAFLD, no drugs have...
5.
Fang D, Xie H, Hu T, Shan H, Li M
Front Cell Dev Biol
. 2021 Jul;
9:685625.
PMID: 34235149
Autophagy is an evolutionarily conserved catabolic process that is essential for maintaining cellular, tissue, and organismal homeostasis. Autophagy-related () genes are indispensable for autophagosome formation. is one of the key...