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Huajian Chen

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Articles 63
Citations 331
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Recent Articles
1.
Huang L, Liang Z, Chen H
Int J Behav Nutr Phys Act . 2025 Mar; 22(1):31. PMID: 40065345
Background: Frailty has become an important health problem in the middle-aged and older people population. Physical activity (PA) is a key intervention for frailty prevention and management. However, studies of...
2.
Lin J, Shen H, Yang W, Zhang G, Sun J, Shen W, et al.
Front Aging Neurosci . 2025 Feb; 17:1510781. PMID: 39906714
Background: Obesity, through mechanisms such as insulin resistance and systemic low-grade inflammation, can damage the central nervous system and impair cognitive function. Weight-adjusted waist index (WWI) is a novel measure...
3.
Zeng T, Lu C, Wang M, Chen H, Yoshitomi T, Kawazoe N, et al.
J Mater Chem B . 2025 Jan; 13(6):2180-2191. PMID: 39803934
The colon possesses a unique physiological environment among human organs, where there is a highly viscous body fluid layer called the mucus layer above colonic epithelial cells. Dysfunction of the...
4.
Zhang C, Yang T, Chen H, Ding X, Chen H, Liang Z, et al.
Cell Death Dis . 2025 Jan; 16(1):9. PMID: 39799112
Radiotherapy is one of the main treatment modalities for advanced hepatocellular carcinoma (HCC). Ferroptosis has been shown to promote the radiosensitivity of HCC cells, but it remains unclear whether epigenetic...
5.
Liang Z, Jin W, Huang L, Chen H
BMC Geriatr . 2024 Nov; 24(1):925. PMID: 39516791
Background: Numerous studies have indicated an obesity paradox in observational research on aging health, where being normal weight or underweight adversely affects cognitive function, while moderate obesity may offer protective...
6.
Sun R, Wang M, Zeng T, Chen H, Yoshitomi T, Takeguchi M, et al.
Bioact Mater . 2024 Nov; 44:205-219. PMID: 39502841
Combining hyperthermia and chemotherapy for maximum anticancer efficacy remains a challenge because drug-tolerant cancer cells often evade this synergistic treatment due to drug resistance and asynchronous drug release. In this...
7.
Liang Z, Jin W, Huang L, Chen H
Front Nutr . 2024 Oct; 11:1459480. PMID: 39464685
Background: The association between obesity indicators and sleep quality remains unclear among elderly Chinese people. Therefore, we aimed to assess this association by utilizing data from the Chinese Longitudinal Healthy...
8.
Huang L, Chen H, Liang Z
Sci Rep . 2024 Oct; 14(1):23227. PMID: 39369089
Frailty is a state that is closely associated with adverse health outcomes in the aging process. The frailty index (FI), which measures frailty in terms of cumulative deficits, has been...
9.
Ma C, Chen J, Ji J, Zheng Y, Liu Y, Wang J, et al.
Biochim Biophys Acta Mol Basis Dis . 2024 Aug; 1870(8):167449. PMID: 39111632
Glioblastoma multiforme (GBM) remains the most lethal central nervous system cancer with poor survival and few targeted therapies. The GBM tumor microenvironment is complex and closely associated with outcomes. Here,...
10.
Yang T, Huang L, He J, Luo L, Guo W, Chen H, et al.
Clin Exp Pharmacol Physiol . 2024 Jul; 51(8):e13907. PMID: 38965675
Objective: Most cases of hepatocellular carcinoma (HCC) arise as a consequence of cirrhosis. In this study, our objective is to construct a comprehensive diagnostic model that investigates the diagnostic markers...