Hsuan-Cheng Huang
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Explore the profile of Hsuan-Cheng Huang including associated specialties, affiliations and a list of published articles.
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Articles
113
Citations
2176
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Recent Articles
1.
Su Y, Huang H, Lin Y, Chuang Y, Sheu S, Lin C
J Transl Med
. 2025 Jan;
23(1):57.
PMID: 39891114
Background: The traditional process of developing new drugs is time-consuming and often unsuccessful, making drug repurposing an appealing alternative due to its speed and safety. Graph neural networks (GCNs) have...
2.
Sun Y, Hsieh C, Wen J, Tseng T, Huang J, Oyang Y, et al.
Biomed Pharmacother
. 2024 Jul;
177:117070.
PMID: 38964180
Predicting drug responses based on individual transcriptomic profiles holds promise for refining prognosis and advancing precision medicine. Although many studies have endeavored to predict the responses of known drugs to...
3.
Lee S, Huang C, Oyang Y, Huang H, Juan H
J Transl Med
. 2024 Jun;
22(1):600.
PMID: 38937794
Background: Interstitial lung disease (ILD) is the primary cause of mortality in systemic sclerosis (SSc), an autoimmune disease characterized by tissue fibrosis. SSc-related ILD (SSc-ILD) occurs more frequently in females...
4.
Wang W, Kao Y, Hsieh C, Tsai S, Cheung C, Huang H, et al.
J Proteome Res
. 2023 Dec;
23(1):301-315.
PMID: 38064546
Mitochondrial division inhibitor 1 (Mdivi-1) is a well-known synthetic compound aimed at inhibiting dynamin-related protein 1 (Drp1) to suppress mitochondrial fission, making it a valuable tool for studying mitochondrial dynamics....
5.
Hsieh C, Huang C, Cheng Y, Hsu C, Hsu W, Chung Y, et al.
Biomed Pharmacother
. 2023 Sep;
166:115429.
PMID: 37673018
Neuroblastoma, a childhood cancer affecting the sympathetic nervous system, continues to challenge the development of potent treatments due to the limited availability of druggable targets for this aggressive illness. Recent...
6.
IFF: Identifying key residues in intrinsically disordered regions of proteins using machine learning
Ho W, Huang H, Huang J
Protein Sci
. 2023 Jul;
32(9):e4739.
PMID: 37498545
Conserved residues in protein homolog sequence alignments are structurally or functionally important. For intrinsically disordered proteins or proteins with intrinsically disordered regions (IDRs), however, alignment often fails because they lack...
7.
Su Y, Liu Y, Huang H, Lin C
J Transl Med
. 2023 Jul;
21(1):485.
PMID: 37475016
Background: The nuclear factor kappa B (NFκB) regulatory pathways downstream of tumor necrosis factor (TNF) play a critical role in carcinogenesis. However, the widespread influence of NFκB in cells can...
8.
Kao Y, Chang Y, Lai C, Chang N, Huang C, Chen C, et al.
Commun Biol
. 2023 Jun;
6(1):642.
PMID: 37322056
Ectopic ATP synthase on the plasma membrane (eATP synthase) has been found in various cancer types and is a potential target for cancer therapy. However, whether it provides a functional...
9.
Chang Y, Yang T, Chen M, Liaw Y, Yin C, Lin-Yan X, et al.
Commun Biol
. 2023 Apr;
6(1):427.
PMID: 37072500
Ectopic ATP synthase complex (eATP synthase), located on cancer cell surface, has been reported to possess catalytic activity that facilitates the generation of ATP in the extracellular environment to establish...
10.
Tu Y, Juan H, Huang H
Brief Bioinform
. 2023 Jan;
24(2).
PMID: 36653899
Gene regulatory networks govern complex gene expression programs in various biological phenomena, including embryonic development, cell fate decisions and oncogenesis. Single-cell techniques are increasingly being used to study gene expression,...