Howard Williams
Overview
Explore the profile of Howard Williams including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
146
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0
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Recent Articles
11.
Simkhada D, Zhang H, Mori S, Williams H, Watanabe C
Beilstein J Org Chem
. 2013 Sep;
9:1768-73.
PMID: 24062841
At least 65% of all small molecule drugs on the market today are natural products, however, re-isolation of previously identified and characterized compounds has become a serious impediment to the...
12.
Li J, Cisar J, Zhou C, Vera B, Williams H, Rodriguez A, et al.
Nat Chem
. 2013 May;
5(6):510-7.
PMID: 23695633
Natural products have a venerable history of, and enduring potential for the discovery of useful biological activity. To fully exploit this, the development of chemical methodology that can functionalize unique...
13.
Hwang S, Shao Q, Williams H, Hilty C, Gao Y
J Phys Chem B
. 2011 May;
115(20):6653-60.
PMID: 21534580
A combined simulation and experimental study was performed to investigate how methanol affects the structure of a model peptide BBA5. BBA5 forms a stable β-hairpin-α-helix structure in aqueous solutions. Molecular...
14.
Nachman R, Ben Aziz O, Davidovitch M, Kaczmarek K, Zabrocki J, Williams H, et al.
Front Biosci (Elite Ed)
. 2009 Dec;
2(1):195-203.
PMID: 20036870
The pyrokinin/pheromone biosynthesis activating neuropeptide (PK/PBAN) family plays a significant role in the regulation of reproductive and developmental processes in a variety of insects. A transPro, type I beta-turn has...
15.
Taneja-Bageshwar S, Strey A, Zubrzak P, Williams H, Reyes-Rangel G, Juaristi E, et al.
Peptides
. 2008 Jan;
29(2):302-9.
PMID: 18207610
The multifunctional arthropod 'insect kinins' share the evolutionarily conserved C-terminal pentapeptide motif Phe-X1-X2-Trp-Gly-NH2, where X1=His, Asn, Ser, or Tyr and X2=Ser, Pro, or Ala. Eight different analogs of the insect...
16.
Angell S, Bench B, Williams H, Watanabe C
Chem Biol
. 2006 Dec;
13(12):1349-59.
PMID: 17185230
Marine microbial populations collected from the Hawaiian Islands were screened for antimicrobial activity. A blue metabolite was identified from mixed cell cultures, but production was not evident in pure cultures....
17.
Zubrzak P, Williams H, Coast G, Isaac R, Reyes-Rangel G, Juaristi E, et al.
Biopolymers
. 2006 Nov;
88(1):76-82.
PMID: 17117460
Insect neuropeptides of the insect kinin class share a common C-terminal pentapeptide sequence F(1)X(1)(2)X(2)(3)W(4)G(5)-NH(2) (X(2)(3) = P, S, A) and regulate such critical physiological processes as water balance and digestive...
18.
Nachman R, Vercammen T, Williams H, Kaczmarek K, Zabrocki J, Schoofs L
Peptides
. 2005 Jan;
26(1):115-20.
PMID: 15626511
The aliphatic amino diacid alpha-aminosuberic acid can function as an effective, stable mimic of the hydrolysis-susceptible Tyr(SO3H) group in sulfakinin neuropeptide analogs for both hindgut contractile activity in cockroach and...