Hongzhi Cao
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Explore the profile of Hongzhi Cao including associated specialties, affiliations and a list of published articles.
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107
Citations
4086
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Recent Articles
1.
Ye J, Zhong K, Hu Z, Liu C, Li M, Wu P, et al.
Angew Chem Int Ed Engl
. 2024 Dec;
64(7):e202418929.
PMID: 39714328
Owing to the inaccessibility of β1-4-N-acetylgalactosaminyltransferase for direct glycan chain elongation, the enzymatic synthesis of 0-series gangliosides with extended backbones has not been explored. In this study, sialic acid was...
2.
Zhu X, Yao W, Sun N, Chen M, Xia H, Liu C, et al.
Org Lett
. 2024 Oct;
26(44):9580-9585.
PMID: 39450892
Herein, we describe a chemoenzymatic and diversity-oriented approach for the first syntheses of octasaccharide repeating units of the capsular polysaccharides of serovar 15 and serovar 5. The synthetic method features...
3.
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, et al.
Cell
. 2024 Jul;
187(16):4261-4271.e17.
PMID: 38964329
The entry of coronaviruses is initiated by spike recognition of host cellular receptors, involving proteinaceous and/or glycan receptors. Recently, TMPRSS2 was identified as the proteinaceous receptor for HCoV-HKU1 alongside sialoglycan...
4.
Zhang P, Li C, Ma X, Ye J, Wang D, Cao H, et al.
ACS Macro Lett
. 2024 Jul;
13(7):874-881.
PMID: 38949618
The frequent mutations of influenza A virus (IAV) have led to an urgent need for the development of innovative antiviral drugs. Glycopolymers offer significant advantages in biomedical applications owing to...
5.
Yin X, Ye T, Chen H, Liu J, Mu X, Li H, et al.
Microbiol Spectr
. 2024 Jun;
12(8):e0354923.
PMID: 38916335
Importance: This study presents a system-level map of the differences between feces and rectal mucosal microbial communities in samples with colorectal cancer risk. It reveals the unique microecological characteristics of...
6.
Ding H, Zhang X, Guo A, Lee Q, Cai C, Li M, et al.
J Am Chem Soc
. 2024 Apr;
146(17):11811-11822.
PMID: 38635880
The development of novel agents with immunoregulatory effects is a keen way to combat the growing threat of inflammatory storms to global health. To synthesize pseudo-steroidal glycosides tethered by ether...
7.
Liu C, Ye J, Cao H
Acc Chem Res
. 2024 Jan;
PMID: 38286791
ConspectusThe limited availability of structurally well-defined diverse glycans remains a major obstacle for deciphering biological functions as well as biomedical applications of carbohydrates. Despite tremendous progress that has been made...
8.
Hu Z, Zhong K, Cao H
Curr Opin Chem Biol
. 2023 Dec;
78:102417.
PMID: 38141531
Glycosylation is one of the most common post-translational modifications of proteins, which plays essential roles in regulating the biological functions of proteins. Efficient and versatile methods for the synthesis of...
9.
Meng J, Zhu Y, Wang H, Cao H, Mu W
J Agric Food Chem
. 2023 Jan;
71(5):2234-2243.
PMID: 36700801
Human milk oligosaccharides (HMOs) have unique beneficial effects for infants and are considered as the new gold standard for premium infant formula. They are a collection of unconjugated glycans, and...
10.
Su L, Xian J, Fu S, Zhu Y, Cao H, Feng Z, et al.
Nanoscale
. 2022 Dec;
15(1):350-355.
PMID: 36504372
Mitochondria targeting complexes are widely utilized as photosensitizers in photodynamic therapy. However, the mechanisms by which they regulate reactive oxygen species (ROS) production at the molecular level and their influence...