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Hongru Hu

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Articles 6
Citations 21
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Recent Articles
1.
Hu H, Quon G
Nat Commun . 2024 Nov; 15(1):9932. PMID: 39548084
Multimodal single-cell assays profile multiple sets of features in the same cells and are widely used for identifying and mapping cell states between chromatin and mRNA and linking regulatory elements...
2.
Ren Y, Wang X, Zhang S, Hu H, Quicksall Z, Lee S, et al.
Sci Rep . 2023 Oct; 13(1):16855. PMID: 37803069
Mounting evidence highlights the crucial role of aging in the pathogenesis of Alzheimer's disease (AD). We have previously explored human apoE-targeted replacement mice across different ages and identified distinct molecular...
3.
Johansen N, Hu H, Quon G
Nat Commun . 2023 Aug; 14(1):5192. PMID: 37626024
Multi-modal single cell RNA assays capture RNA content as well as other data modalities, such as spatial cell position or the electrophysiological properties of cells. Compared to dedicated scRNA-seq assays...
4.
Wang Y, Zhang W, Wu Y, Qu C, Hu H, Lee T, et al.
STAR Protoc . 2023 May; 4(2):102259. PMID: 37133992
Conventional approaches for screening anticancer drugs rely on chemical reactions, which are time consuming, labor intensive, and costly. Here, we present a protocol for label-free and high-throughput assessment of drug...
5.
Wang Y, Zhang W, Yip H, Qu C, Hu H, Chen X, et al.
Patterns (N Y) . 2023 Mar; 4(2):100686. PMID: 36873901
As a measure of cytotoxic potency, half-maximal inhibitory concentration (IC50) is the concentration at which a drug exerts half of its maximal inhibitory effect against target cells. It can be...
6.
Brovero S, Fortier J, Hu H, Lovejoy P, Newell N, Palmateer C, et al.
Elife . 2021 Feb; 10. PMID: 33616528
reproductive behaviors are directed by neurons. A reanalysis of genomic studies shows that genes encoding and immunoglobulin superfamily (IgSF) members are expressed in neurons. We find that each and (...