Hongbin Deng
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Explore the profile of Hongbin Deng including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
1571
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Recent Articles
1.
Sun C, Cheng Y, Dong J, Hu L, Zhang Y, Shen H, et al.
J Med Chem
. 2024 Dec;
68(1):156-173.
PMID: 39731560
Inhibiting the activity of immune checkpoint proteins to reignite the antitumor activity of immune cells has emerged as a pivotal strategy. PD-L1 and VISTA, as critical proteins governing immune regulation,...
2.
Ma K, Cheng B, Xu X, Zhang L, Ruan R, Deng H, et al.
Nanotechnology
. 2024 Nov;
36(7).
PMID: 39577013
The irritation and adhesion of wound healing biomaterials to wet wounds should be addressed for achieving effective wound healing. In this study, a stable multifunctional hydrogels (BGs/HA suspension gels) were...
3.
Zhang X, Ma C, Lu Y, Wang J, Yun H, Jiang H, et al.
Cell Mol Immunol
. 2024 Sep;
21(11):1282-1295.
PMID: 39256480
The transcription factor Pax5 activates genes essential for B-cell development and function. However, the regulation of Pax5 expression remains elusive. The adaptor Rack1 can interact with multiple transcription factors and...
4.
Lin Y, Shen Y, He R, Wang Q, Deng H, Cheng S, et al.
J Diabetes Investig
. 2024 Jul;
15(10):1403-1409.
PMID: 38989799
Introduction: The fasting blood glucose test is widely used for diabetes screening. However, it may fail to detect early-stage diabetes characterized by elevated postprandial glucose levels. Hence, we developed and...
5.
Wei W, Zeng Q, Wang Y, Guo X, Fan T, Li Y, et al.
Acta Pharm Sin B
. 2024 Mar;
14(3):1477.
PMID: 38486984
[This corrects the article DOI: 10.1016/j.apsb.2022.12.009.].
6.
Xiao D, Liu L, Xie F, Dong J, Wang Y, Xu X, et al.
Angew Chem Int Ed Engl
. 2024 Feb;
63(16):e202310318.
PMID: 38369681
Existing antibody-drug conjugate (ADC) linkers, whether cleavable or non-cleavable, are designed to release highly toxic payloads or payload derivatives upon internalisation of the ADCs into cells. However, clinical studies have...
7.
Xiao M, Deng H, Mao W, Liu Y, Yang Q, Liu Y, et al.
PLoS One
. 2023 Nov;
18(11):e0294779.
PMID: 38011086
Background: Sepsis is characterized by upregulated lipolysis in adipose tissue and a high blood triglyceride (TG) level. It is still debated whether serum TG level is related to mortality in...
8.
Wang H, Chen F, Wang S, Li Y, Liu T, Li Y, et al.
Front Pharmacol
. 2023 Nov;
14:1251731.
PMID: 37954857
Hand, foot, and mouth disease (HFMD) caused by enterovirus A71 (EV-A71) infection, currently lacks specific preventive and therapeutic interventions. Here, we demonstrated that Pien Tze Huang (PZH) could dose-dependently inhibit...
9.
Deng H, Yu X, Liu Y, Li W, Fan J
Chronobiol Int
. 2023 Oct;
40(9):1251-1260.
PMID: 37781772
Disrupted circadian temperature rhythm is commonly observed in elderly patients in the intensive care unit (ICU), but the association between circadian temperature rhythm and mortality in elderly patients is unclear....
10.
Kuang Z, Liu X, Zhang N, Dong J, Sun C, Yin M, et al.
Cell Death Differ
. 2023 Sep;
30(10):2249-2264.
PMID: 37670038
The abnormal upregulation of programmed death ligand-1 (PD-L1) on tumor cells impedes T-cell mediated cytotoxicity through PD-1 engagement, and further exploring the mechanisms regulation of PD-L1 in cancers may enhance...