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Hong-Wei Shao

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Articles 13
Citations 72
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Recent Articles
1.
Wang Y, Wang H, Jian Y, Luo Z, Shao H, Zhang W
Hum Gene Ther . 2021 Dec; 33(7-8):358-370. PMID: 34963339
The clustered regularly interspaced short palindromic repeats (CRISPR) system is inarguably the most valuable gene editing tool ever discovered. Currently, three classes of CRISPR-based genome editing systems have been developed...
2.
Li Q, Wang H, Gong C, Chen Z, Yang J, Shao H, et al.
Indian J Microbiol . 2021 Jan; 61(1):91-95. PMID: 33505098
Immunotherapy based on genetic modification of T cells has played an important role in the treatment of tumors and viral infections. Moreover, adenoviral vectors engineered with improved safety due to...
3.
Wang H, Lu H, Lei Y, Gong C, Chen Z, Luan Y, et al.
Mol Ther Methods Clin Dev . 2020 Jul; 18:390-401. PMID: 32695841
Development of the CRISPR-Cas9 gene-editing system has given rise to a new era of gene editing with wide applications in biology, medicine, agriculture, and other fields. However, the overexpression of...
4.
Xiang J, Huang J, Xu C, He M, Xu P, Zhang D, et al.
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(9):1752-1756. PMID: 29082701
MicroRNAs(miRNA) are small non-coding RNAs that regulate the expression of protein coding genes by repressing translation of protein coding mRNA or enhancing mRNA degradation. Its functions have attracted more and...
5.
Gu Y, Cui Z, Shao H, Ye Y, Gu A
J Orthop Surg Res . 2017 Feb; 12(1):25. PMID: 28178992
Background: We designed an easy posterolateral transforaminal endoscopic decompression technique, termed PTES, for radiculopathy secondary to lumbar disc herniation. The purpose of the study is to describe the technique of...
6.
Zhang W, Shao H, Wu F, Xie X, Li Z, Bo H, et al.
Sci Rep . 2016 Mar; 6:22688. PMID: 26972139
Adoptive transfer of genetically-modified T cells is a promising approach for treatment of both human malignancies and viral infections. Due to its ability to efficiently infect lymphocytes, the chimeric adenovirus...
7.
Shao H, He M, Chen J, Chen H, Xiang J, Huang S
Zhong Yao Cai . 2016 Mar; 38(7):1449-53. PMID: 26946842
Objective: To extract microRNA(miRNA) from Glycyrrhiza uralensis(liquorice) decoction and to explore its effect on mmune cells. Methods: With dried processed liquorice, the water decoction was prepared according to the conventional...
8.
Yuan Y, Lu X, Tao C, Chen X, Shao H, Huang S
In Vitro Cell Dev Biol Anim . 2013 Aug; 49(10):752-8. PMID: 23949777
The ability of mesenchymal stem cells (MSCs) to preserve cancer cells potentially constitutes the adverse effect of MSC-based cell therapy in the context of hematologic malignancy. In an effort to...
9.
Zhang W, Wu F, Shao H, Wang T, Huang X, Li W, et al.
J Virol Methods . 2013 Aug; 194(1-2):52-9. PMID: 23933078
Adoptive therapy using T cells modified with tumour antigen-specific T cell receptor (TCR) genes has become a popular area of research in tumour biotherapy research. However, the efficiency of this...
10.
Shen H, Shao H, Chen X, Wu F, Wang H, Huang Z, et al.
Cancer Immunol Immunother . 2012 Aug; 62(2):393-403. PMID: 22926105
Peptide vaccine based on tumor-associated antigen (TAA), which usually belongs to self-antigen with poor immunogenicity, has been considered as an attractive option for treatment of malignant tumors. The ideal TAA...