Holly R Chinnery
Overview
Explore the profile of Holly R Chinnery including associated specialties, affiliations and a list of published articles.
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61
Citations
1176
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Recent Articles
1.
Zhu Y, Wu M, Li D, Habgood M, Chinnery H, Schneider-Futschik E
J Cyst Fibros
. 2024 Dec;
24(1):21-25.
PMID: 39643543
Background And Objective: Elexacaftor-tezacaftor-ivacaftor (ETI) is a drug treatment for cystic fibrosis that is debatable for use in pregnant women. Fetal ocular changes following prenatal exposure and while breastfeeding to...
2.
Bedggood P, Wu M, Zhang X, Rajan R, Wu C, Karunaratne S, et al.
Biomed Opt Express
. 2024 Nov;
15(11):6277-6298.
PMID: 39553868
confocal microscopy (IVCM) is a widely used technique for imaging the cornea of the eye with a confocal scanning light ophthalmoscope. Cellular resolution and high contrast are achieved without invasive...
3.
Huang X, Fowler C, Li Y, Li Q, Sun J, Pan Y, et al.
Nat Commun
. 2024 Sep;
15(1):7998.
PMID: 39266542
Impaired clearance of amyloid β (Aβ) in late-onset Alzheimer's disease (AD) affects disease progression. The role of peripheral monocytes in Aβ clearance from the central nervous system (CNS) is unclear....
4.
Schneider-Futschik E, Zhu Y, Li D, Habgood M, Nguyen B, Pankonien I, et al.
Prog Retin Eye Res
. 2024 Sep;
103:101299.
PMID: 39245300
Cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that plays a crucial role in various human organs, including the respiratory and digestive systems. Dysfunctional CFTR is the key variant...
5.
Wu M, Fletcher E, Chinnery H, Downie L, Mueller S
Nat Rev Immunol
. 2024 Aug;
24(12):896-911.
PMID: 39215057
Balanced immune responses in the eyes are crucial to preserve vision. The ocular immune system has long been considered distinct, owing to the so-called 'immune privilege' of its component tissues....
6.
Britten-Jones A, Wu M, Roberts L, MacIsaac R, Jiao H, Craig J, et al.
Ocul Surf
. 2024 Aug;
34:309-316.
PMID: 39153598
Aims: To investigate tear neuropeptide Y (NPY) and substance P concentrations in individuals with type 1 diabetes, comparing those with and without both diabetic retinopathy (DR) and peripheral neuropathy. Methods:...
7.
Wu M, Zhang X, Karunaratne S, Lee J, Lampugnani E, Selva K, et al.
Ophthalmology
. 2024 May;
131(10):1185-1195.
PMID: 38703795
Purpose: Defining how the in vivo immune status of peripheral tissues is shaped by the external environment has remained a technical challenge. We recently developed Functional in vivo confocal microscopy...
8.
Rajan R, Makrai E, Lee J, Singh S, Chinnery H, Downie L
Ocul Surf
. 2024 Apr;
33:80-98.
PMID: 38688453
Corneal neuropathy involves corneal nerve damage that disrupts ocular surface integrity, negatively impacting quality-of-life from pain and impaired vision. Any ocular or systemic condition that damages the trigeminal nerve can...
9.
Harris S, Chinnery H, Semple B, Mychasiuk R
J Neurotrauma
. 2024 Mar;
41(15-16):1853-1870.
PMID: 38497766
Traumatic brain injuries (TBIs) are a large societal and individual burden. In the first year of life, the vast majority of these injuries are the result of inflicted abusive events...
10.
Zhu Y, Li D, Reyes-Ortega F, Chinnery H, Schneider-Futschik E
Front Pharmacol
. 2023 Oct;
14:1265138.
PMID: 37795027
Highly effective cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulator therapies (HEMT), including elexacaftor-tezacaftor-ivacaftor, correct the underlying molecular defect causing CF. HEMT decreases general symptom burden by improving clinical metrics...