Holly Kemberling
Overview
Explore the profile of Holly Kemberling including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
7960
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Recent Articles
1.
Cheung L, Chen L, Oke T, Schaffer T, Boudadi K, Ngo J, et al.
J Immunother Cancer
. 2021 Jun;
9(6).
PMID: 34103354
Undifferentiated pleomorphic sarcoma (UPS), an aggressive soft-tissue sarcoma of adults, has been characterized by low tumor mutational burden (TMB) and high copy number alterations. Clinical trials of programmed death-1 (PD-1)...
2.
Le D, Durham J, Smith K, Wang H, Bartlett B, Aulakh L, et al.
Science
. 2017 Jun;
357(6349):409-413.
PMID: 28596308
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of somatic mutations. In a proof-of-concept study, we previously showed that colorectal cancers with mismatch repair deficiency were...
3.
Le D, Uram J, Wang H, Bartlett B, Kemberling H, Eyring A, et al.
N Engl J Med
. 2015 Jun;
372(26):2509-20.
PMID: 26028255
Background: Somatic mutations have the potential to encode "non-self" immunogenic antigens. We hypothesized that tumors with a large number of somatic mutations due to mismatch-repair defects may be susceptible to...