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Holger Rothkegel

Explore the profile of Holger Rothkegel including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 190
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Recent Articles
1.
Syk M, Tornvind E, Gallwitz M, Fallmar D, Amandusson A, Rothkegel H, et al.
Transl Psychiatry . 2024 Jul; 14(1):304. PMID: 39048548
There is growing evidence suggesting that immunological mechanisms play a significant role in the development of psychiatric symptoms in certain patient subgroups. However, the relationship between clinical red flags for...
2.
Katsarogiannis E, Axelson H, Berntsson S, Rothkegel H, Burman J
Mult Scler Relat Disord . 2024 Jan; 83:105447. PMID: 38242050
Objective: To investigate the effect of autologous hematopoietic stem cell transplantation (AHSCT) on functional aspects of the nervous system assessed by visual (VEP), somatosensory (SEP), and motor (MEP) evoked potentials...
3.
Ambrus G, Chaieb L, Stilling R, Rothkegel H, Antal A, Paulus W
Neurosci Lett . 2016 Jan; 616:98-104. PMID: 26826607
The measurement of the motor evoked potential (MEP) amplitudes using single pulse transcranial magnetic stimulation (TMS) is a common method to observe changes in motor cortical excitability. The level of...
4.
Laczo B, Antal A, Rothkegel H, Paulus W
Restor Neurol Neurosci . 2014 Mar; 32(3):403-10. PMID: 24576783
Purpose: Transcranial random noise stimulation (tRNS) can increase the excitability of hand area of the primary motor cortex (M1). The aim of this study was to compare the efficacy of...
5.
Lang N, Rothkegel H, Terney D, Antal A, Paulus W
Epilepsy Res . 2013 Oct; 107(3):302-5. PMID: 24139854
Minocycline has efficacy to alleviate seizure activity in animal models of epilepsy. Among other mechanisms it has been postulated that minocycline can inhibit microglial activation and develop beneficial effects by...
6.
Lang N, Rothkegel H, Peckolt H, Deuschl G
Seizure . 2013 Jun; 22(9):726-30. PMID: 23778157
Purpose: Lacosamide (LCM) and carbamazepine (CBZ) are antiepileptic drugs both acting on neuronal voltage-gated sodium channels. Patch-clamp studies demonstrated significant differences in how LCM and CBZ affect neuronal membrane excitability....
7.
Sommer M, Rummel M, Norden C, Rothkegel H, Lang N, Paulus W
J Neurophysiol . 2013 Mar; 109(12):3060-6. PMID: 23536708
Our knowledge about the mechanisms of human motor cortex facilitation induced by repetitive transcranial magnetic stimulation (rTMS) is still incomplete. Here we used pharmacological conditioning with carbamazepine, dextrometorphan, lorazepam, and...
8.
Sommer M, Norden C, Schmack L, Rothkegel H, Lang N, Paulus W
Brain Stimul . 2012 Aug; 6(3):363-70. PMID: 22885142
Background: Directional sensitivity is relevant for the excitability threshold of the human primary motor cortex, but its importance for externally induced plasticity is unknown. Objective: To study the influence of...
9.
Sommer M, Gileles E, Knappmeyer K, Rothkegel H, Polania R, Paulus W
Clin Neurophysiol . 2011 Aug; 123(2):351-7. PMID: 21862399
Objective: We sought to elucidate the influence of centrally active drugs on interhemispheric inhibition (IHI) between primary motor cortices in healthy humans. Methods: We therefore studied IHI before and 2h...
10.
Lang N, Rothkegel H, Reiber H, Hasan A, Sueske E, Tergau F, et al.
Cereb Cortex . 2011 Feb; 21(10):2299-306. PMID: 21350047
Circadian rhythms exert powerful influence on various aspects of human physiology and behavior. Here, we tested changes of human cerebral cortex excitability over the course of the day with transcranial...