Holger Peter Behrsing
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Explore the profile of Holger Peter Behrsing including associated specialties, affiliations and a list of published articles.
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3
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7
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Recent Articles
1.
de Avila R, Muller I, Barlow H, Middleton A, Theiventhran M, Basili D, et al.
Front Toxicol
. 2025 Mar;
7:1426132.
PMID: 40061084
Introduction: This work evaluated a non-animal toolbox to be used within a next-generation risk assessment (NGRA) framework to assess chemical-induced lung effects using human upper and lower respiratory tract models,...
2.
Sadekar N, Behrsing H, Hansen T, Patel V, Paulo H, Rae A, et al.
Toxics
. 2025 Jan;
13(1).
PMID: 39853033
There is increased interest in developing non-animal test systems for inhalation exposure safety assessments. However, defined methodologies are absent for predicting local respiratory effects from inhalation exposure to irritants. The...
3.
Marimoutou M, Patel V, Kim J, Schaible N, Alvarez J, Hughes J, et al.
Toxics
. 2024 Sep;
12(9).
PMID: 39330565
Human precision-cut lung slices (hPCLS) prepared from fibrotic lungs recapitulate the pathophysiological hallmarks of fibrosis. These hallmark features can also be induced by treating non-fibrotic hPCLS with a fibrotic cocktail...
4.
Behrsing H, Furniss M, Robillard K, Tomaszewski J, Parchment R
Cancer Chemother Pharmacol
. 2009 Sep;
65(6):1083-91.
PMID: 19727731
2-Amino-O4-benzylpteridine derivatives inactivate the human DNA repair protein O6-alkylguanine-DNA alkyltransferase and have been tested as modulators of alkylating agent chemotherapy. Recently, the therapeutic potential of O4-benzylfolate (O4BF) in modulating bis-chloroethylnitrosourea...
5.
Behrsing H, Vulliet P
J Neurosci Res
. 2004 Sep;
78(1):64-74.
PMID: 15372494
In 1999, we reported new observations that several compounds, including ATP, enhance neurite expression in PC12 cells when coapplied with nerve growth factor (NGF). Because purinergic and NGF signaling have...