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Holger Ludwig

Explore the profile of Holger Ludwig including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 887
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Recent Articles
1.
Volz A, Jany S, Freudenstein A, Lantermann M, Ludwig H, Sutter G
Viruses . 2018 Jan; 10(1). PMID: 29300297
The highly attenuated Modified Vaccinia virus Ankara (MVA) lacks most of the known vaccinia virus (VACV) virulence and immune evasion genes. Today MVA can serve as a safety-tested next-generation smallpox...
2.
Schneider N, Ludwig H, Nick P
J Exp Bot . 2015 Mar; 66(7):2001-11. PMID: 25779700
Detyrosination of α-tubulin seems to be conserved in all eukaryotes. However, its biological function in plants has remained obscure. A conserved C-terminal tyrosine is removed by a still unidentified tubulin-tyrosine...
3.
Ferrer P, Potthoff S, Kirschnek S, Gasteiger G, Kastenmuller W, Ludwig H, et al.
PLoS Pathog . 2011 Jun; 7(6):e1002083. PMID: 21698224
Viral infection is a stimulus for apoptosis, and in order to sustain viral replication many viruses are known to carry genes encoding apoptosis inhibitors. F1L, encoded by the orthopoxvirus modified...
4.
Backes S, Sperling K, Zwilling J, Gasteiger G, Ludwig H, Kremmer E, et al.
J Gen Virol . 2009 Oct; 91(Pt 2):470-82. PMID: 19846675
Vaccinia virus (VACV) infection induces phosphorylation of eukaryotic translation initiation factor 2alpha (eIF2alpha), which inhibits cellular and viral protein synthesis. In turn, VACV has evolved the capacity to antagonize this...
5.
Trilling M, Le V, Zimmermann A, Ludwig H, Pfeffer K, Sutter G, et al.
J Virol . 2009 Feb; 83(8):3684-95. PMID: 19211768
Vaccinia virus (VACV) replicates in mouse and human fibroblasts with comparable kinetics and efficiency, yielding similar titers of infectious progeny. Here we demonstrate that gamma interferon (IFN-gamma) but not IFN-alpha...
6.
Waibler Z, Anzaghe M, Frenz T, Schwantes A, Pohlmann C, Ludwig H, et al.
J Virol . 2008 Dec; 83(4):1563-71. PMID: 19073732
Poxviruses such as virulent vaccinia virus (VACV) strain Western Reserve encode a broad range of immune modulators that interfere with host responses to infection. Upon more than 570 in vitro...
7.
Waibler Z, Anzaghe M, Ludwig H, Akira S, Weiss S, Sutter G, et al.
J Virol . 2007 Sep; 81(22):12102-10. PMID: 17855554
Modified vaccinia virus Ankara (MVA) is a highly attenuated vaccinia virus strain undergoing clinical evaluation as a replication-deficient vaccine vector against various infections and tumor diseases. To analyze the basis...
8.
Ludwig H, Suezer Y, Waibler Z, Kalinke U, Schnierle B, Sutter G
J Gen Virol . 2006 Apr; 87(Pt 5):1145-1155. PMID: 16603515
Infection of human cells with modified vaccinia virus Ankara (MVA) activates the typical cascade-like pattern of viral early-, intermediate- and late-gene expression. In contrast, infection of human HeLa cells with...
9.
Kastenmuller W, Drexler I, Ludwig H, Erfle V, Peschel C, Bernhard H, et al.
Virology . 2006 Apr; 350(2):276-88. PMID: 16595141
Vector-infected dendritic cells (DC) are evaluated for antigen delivery in experimental therapy of cancer and infectious diseases. Here, we investigated infections of immature or mature, monocyte-derived human DC with recombinant...
10.
Blencke H, Reif I, Commichau F, Detsch C, Wacker I, Ludwig H, et al.
Arch Microbiol . 2006 Jan; 185(2):136-46. PMID: 16395550
The tricarboxylic acid (TCA) cycle is one of the major routes of carbon catabolism in Bacillus subtilis. The syntheses of the enzymes performing the initial reactions of the cycle, citrate...