Holger Hagele
Overview
Explore the profile of Holger Hagele including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
318
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0
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Recent Articles
1.
Volker L, Kaufeld J, Balduin G, Merkel L, Kuhne L, Eichenauer D, et al.
J Thromb Haemost
. 2023 Jan;
21(3):559-572.
PMID: 36696206
Background: The von Willebrand factor-directed nanobody caplacizumab has greatly changed the treatment of immune thrombotic thrombocytopenic purpura (iTTP) in recent years. Data from randomized controlled trials established efficacy and safety....
2.
Kuhne L, Kaufeld J, Volker L, Wendt R, Schonermarck U, Hagele H, et al.
J Thromb Haemost
. 2022 Jan;
20(4):951-960.
PMID: 35000278
Background: The anti-von Willebrand factor (VWF) nanobody caplacizumab directly prevents the fatal microthrombi formation in immune-mediated thrombotic thrombocytopenic purpura (iTTP), thereby adding a new therapeutic principle to the treatment of...
3.
Kuhne L, Volker L, Hagmann H, Hagele H, Osterholt T, Eichenauer D, et al.
Br J Haematol
. 2021 Sep;
196(3):e30-e33.
PMID: 34585743
No abstract available.
4.
Allam R, Scherbaum C, Darisipudi M, Mulay S, Hagele H, Lichtnekert J, et al.
J Am Soc Nephrol
. 2012 Jun;
23(8):1375-88.
PMID: 22677551
In AKI, dying renal cells release intracellular molecules that stimulate immune cells to secrete proinflammatory cytokines, which trigger leukocyte recruitment and renal inflammation. Whether the release of histones, specifically, from...
5.
Hagele H, Allam R, Pawar R, Reichel C, Krombach F, Anders H
Am J Pathol
. 2009 Oct;
175(5):1896-904.
PMID: 19834059
Viral DNA induces potent antiviral immunity by activating dendritic cells; however, the mechanism governing viral DNA-mediated triggering or aggravation of glomerulonephritis is unknown. Glomerular endothelial cells (GEnCs) do not express...
6.
Hagele H, Allam R, Pawar R, Anders H
Nephrol Dial Transplant
. 2009 Jul;
24(11):3312-8.
PMID: 19608629
Background: The molecular pathomechanisms by which viral infections trigger glomerulonephritis remain elusive. In the glomerulus, glomerular endothelial cells (GEnC) first interact with circulating viral particles; hence, we hypothesized that viral...