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Hjordis Czesnick

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Articles 8
Citations 280
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Recent Articles
1.
Garditz K, Czesnick H
Planta Med . 2024 May; 90(9):726-735. PMID: 38754434
Taxol (common name: paclitaxel) is an extremely important component of drugs for the treatment of various cancers. Thirty years after the discovery of its effectiveness, a metabolic precursor of Taxol...
2.
Brzezinka K, Altmann S, Czesnick H, Nicolas P, Gorka M, Benke E, et al.
Elife . 2016 Sep; 5. PMID: 27680998
Plants as sessile organisms can adapt to environmental stress to mitigate its adverse effects. As part of such adaptation they maintain an active memory of heat stress for several days...
3.
Czesnick H, Lenhard M
Plant J . 2016 Jul; 88(4):570-583. PMID: 27447095
Polyadenylation is a critical 3'-end processing step during maturation of pre-mRNAs, and the length of the poly(A) tail affects mRNA stability, nuclear export and translation efficiency. The Arabidopsis thaliana genome...
4.
Kappel C, Trost G, Czesnick H, Ramming A, Kolbe B, Vi S, et al.
PLoS Genet . 2015 Aug; 11(8):e1005474. PMID: 26305463
The poly(A) tail at 3' ends of eukaryotic mRNAs promotes their nuclear export, stability and translational efficiency, and changes in its length can strongly impact gene expression. The Arabidopsis thaliana...
5.
Czesnick H, Lenhard M
Cold Spring Harb Perspect Biol . 2015 Aug; 7(8):a019190. PMID: 26238357
To achieve optimal functionality, plant organs like leaves and petals have to grow to a certain size. Beginning with a limited number of undifferentiated cells, the final size of an...
6.
Trost G, Vi S, Czesnick H, Lange P, Holton N, Giavalisco P, et al.
Plant J . 2013 Dec; 77(5):688-99. PMID: 24372773
Polyadenylation of pre-mRNAs by poly(A) polymerase (PAPS) is a critical process in eukaryotic gene expression. As found in vertebrates, plant genomes encode several isoforms of canonical nuclear PAPS enzymes. In...
7.
Vi S, Trost G, Lange P, Czesnick H, Rao N, Lieber D, et al.
Proc Natl Acad Sci U S A . 2013 Aug; 110(34):13994-9. PMID: 23918356
Polyadenylation of pre-mRNAs is critical for efficient nuclear export, stability, and translation of the mature mRNAs, and thus for gene expression. The bulk of pre-mRNAs are processed by canonical nuclear...
8.
Kazamia E, Czesnick H, Nguyen T, Croft M, Sherwood E, Sasso S, et al.
Environ Microbiol . 2012 Apr; 14(6):1466-76. PMID: 22463064
Many algae are auxotrophs for vitamin B(12) (cobalamin), which they need as a cofactor for B(12) -dependent methionine synthase (METH). Because only prokaryotes can synthesize the cobalamin, they must be...