Hisham Mehanna
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Explore the profile of Hisham Mehanna including associated specialties, affiliations and a list of published articles.
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160
Citations
3396
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Recent Articles
11.
Mehanna H, Nankivell P, Boelaert K, Woolley R, Sharma N, Sidhu P, et al.
J Clin Endocrinol Metab
. 2024 Oct;
PMID: 39359050
Introduction: ElaTION is a large multi-centre pragmatic randomised controlled trial, performed in 18 secondary/tertiary hospitals across England, comparing elastography ultrasound-guided fine needle aspiration cytology (EUS-FNAC) with ultrasound-guided FNAC (US-FNAC) alone...
12.
Brooks J, Zheng Y, Hunter K, Willcox B, Dunn J, Nankivell P, et al.
Front Oncol
. 2024 Sep;
14:1428741.
PMID: 39328208
Background: The incidence of oropharyngeal cancer (OPC) is increasing, due mainly to a rise in Human Papilloma Virus (HPV)-mediated disease. HPV-mediated OPC has significantly better prognosis compared with HPV-negative OPC,...
13.
von Buchwald C, Jakobsen K, Fenger Carlander A, Tous S, Gronhoj C, Rasmussen J, et al.
Eur J Cancer
. 2024 Sep;
211:114329.
PMID: 39293346
Purpose: The assessment of p16INK4a (p16) in oropharyngeal squamous cell carcinoma (OPSCC) has been incorporated into tumor classification, as p16 has been shown to impact survival probability. However, a recent...
14.
Mehanna H, Deeks J, Boelaert K, Madani G, Sidhu P, Nankivell P, et al.
Health Technol Assess
. 2024 Sep;
28(46):1-51.
PMID: 39252469
Background: Strain and shear wave elastography which is commonly used with concurrent real-time imaging known as real-time ultrasound shear/strain wave elastography is a new diagnostic technique that has been reported...
15.
Payne K, Suriyanarayanan H, Brooks J, Mehanna H, Nankivell P, Gendoo D
Oral Oncol
. 2024 Sep;
158:107011.
PMID: 39236578
Liquid biopsy profiling is gaining increasing promise towards biomarker-led identification and disease stratification of tumours, particularly for tumours displaying significant intra-tumoural heterogeneity (ITH). For head and neck squamous cell carcinoma...
16.
Kong A, Kirkham A, Savage J, Mant R, Lax S, Good J, et al.
BJC Rep
. 2024 Sep;
2(1):6.
PMID: 39220748
Background: Pre-clinical studies suggest AZD1775, a WEE1 kinase inhibitor, potentiates the activity of various chemotherapeutic agents. Methods: WISTERIA was a prospective, parallel two-group, open-label, dose-finding, phase I clinical trial. Eligible...
17.
Nankivell P, Gaunt P, Gaunt C, Sissons J, Liaskou E, Jefferson Y, et al.
BMC Cancer
. 2024 Jul;
24(1):861.
PMID: 39026293
No abstract available.
18.
Nankivell P, Gaunt P, Gaunt C, Sissons J, Liaskou E, Jefferson Y, et al.
BMC Cancer
. 2024 Jul;
24(1):823.
PMID: 38987693
Background: Approximately 40% of treated head and neck cancer (HNC) patients develop recurrence. The risk of recurrence declines with time from treatment. Current guidelines recommend clinical follow-up every two months...
19.
Shephard A, Bashir R, Mahmood H, Jahanifar M, Minhas F, Raza S, et al.
NPJ Precis Oncol
. 2024 Jun;
8(1):137.
PMID: 38942998
Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity. Its grading suffers from significant inter-/intra-observer variability, and does not reliably predict malignancy progression,...
20.
Lim A, McDowell L, Hurt C, Le Tourneau C, Homma A, Shenouda G, et al.
Lancet Oncol
. 2024 Jun;
25(7):e318-e330.
PMID: 38936390
Robust time-to-event endpoint definitions are crucial for the assessment of treatment effect and the clinical value of trial interventions. Here, the Head and Neck Cancer International Group investigated endpoint use...