Hiroyasu Inui
Overview
Explore the profile of Hiroyasu Inui including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
51
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Recent Articles
1.
Glinton K, Thakkar A, Jones R, Inui H, Ge Z, Thorp E
J Mol Cell Cardiol
. 2024 Nov;
198():13-20.
PMID: 39592090
Advances in genetic, pharmacologic, and sequencing technology have led to new insight into the role of lymphatics in health and disease. This includes fundamental aspects of the crosstalk between immune...
2.
Nishihara S, Koseki M, Tanaka K, Omatsu T, Saga A, Sawabe H, et al.
Endocr J
. 2024 Sep;
71(11):1055-1067.
PMID: 39261088
We previously demonstrated hepatic, cardiac, and skin inflammation in a high-fat diet-induced steatotic liver disease (SLD) model. However, the molecular mechanism in the kidneys in this model remains unclear. It...
3.
Nishihara S, Koseki M, Tanaka K, Omatsu T, Sawabe H, Inui H, et al.
J Atheroscler Thromb
. 2024 Apr;
31(11):1539-1555.
PMID: 38684403
Aim: A twin study is a valuable tool for elucidating the acquired factors against lifestyle diseases such as dyslipidemia, diabetes mellitus, and obesity. We aimed 1. to investigate the factors...
4.
Inui H, Nishida M, Ichii M, Nakaoka H, Asaji M, Ide S, et al.
J Mol Cell Cardiol
. 2023 Feb;
176:68-83.
PMID: 36739942
Cardiac remodeling has no established therapies targeting inflammation. CD4 T-cell subsets have been reported to play significant roles in healing process after ischemic myocardial injury, but their detailed mechanisms of...
5.
Saga A, Koseki M, Kanno K, Chang J, Higo T, Okuzaki D, et al.
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555497
Patients with psoriasis are at a higher risk of developing nonalcoholic fatty liver disease. We previously identified an oxidized derivative of cholesterol, 7-ketocholesterol (7KC), in diet-induced steatohepatitic mice. Here, we...
6.
Kanno K, Koseki M, Chang J, Saga A, Inui H, Okada T, et al.
Sci Rep
. 2022 Feb;
12(1):2996.
PMID: 35194060
Although patients with nonalcoholic fatty liver disease have been reported to have cardiac dysfunction, and appropriate model has not been reported. We established a novel mouse model of diet-induced steatohepatitis-related...
7.
Tanaka K, Koseki M, Kato H, Miyashita K, Okada T, Kanno K, et al.
J Atheroscler Thromb
. 2022 Feb;
30(1):100-104.
PMID: 35185060
Primary hyperchylomicronemia is characterized by marked hypertriglyceridemia exceeding 1,000 mg/dL. It is caused by dysfunctional mutations in specific genes, namely those for lipoprotein lipase (LPL), glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein...
8.
Chang J, Koseki M, Saga A, Kanno K, Higo T, Okuzaki D, et al.
Front Endocrinol (Lausanne)
. 2021 Mar;
11:614692.
PMID: 33776901
Non-alcoholic fatty liver disease is strongly associated with obese and type 2 diabetes. It has been reported that an oxidized cholesterol, 7-ketocholesterol (7KC), might cause inflammatory response in macrophages and...
9.
Okada T, Sumida M, Ohama T, Katayama Y, Saga A, Inui H, et al.
J Atheroscler Thromb
. 2020 Oct;
28(7):703-715.
PMID: 33028763
Aims: HDL particles have various anti-atherogenic functions, whereas HDL from atherosclerotic patients was demonstrated to be dysfunctional. One possible mechanism for the formation of dysfunctional HDL is the oxidation of...
10.
Zhu Y, Ohama T, Kawase R, Chang J, Inui H, Kanno K, et al.
J Mol Cell Cardiol
. 2019 Dec;
138:197-211.
PMID: 31866375
Aims: Age-related cardiac hypertrophy and subsequent heart failure are predicted to become increasingly serious problems in aging populations. Progranulin (PGRN) deficiency is known to be associated with accelerated aging in...