Hirotaka Komaba
Overview
Explore the profile of Hirotaka Komaba including associated specialties, affiliations and a list of published articles.
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Articles
139
Citations
1797
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Recent Articles
1.
Hamano N, Komaba H, Tanaka H, Takahashi H, Takahashi Y, Hyodo T, et al.
Am J Nephrol
. 2025 Feb;
:1-9.
PMID: 39978330
Introduction: Recent experimental studies have reported that fibroblast growth factor 23 (FGF23) inhibits erythropoiesis by suppressing erythropoietin (EPO) production and downregulating the EPO receptor. Conversely, either endogenous or exogenous EPO...
2.
Imaizumi T, Komaba H, Hamano T, Nangaku M, Murotani K, Hasegawa T, et al.
Clin Kidney J
. 2025 Feb;
18(2):sfae398.
PMID: 39950153
Background: The slope of estimated glomerular filtration rate (eGFR) is a promising surrogate endpoint in patients with chronic kidney disease (CKD). However, current evidence is mainly derived from Western populations...
3.
Ketteler M, Evenepoel P, Holden R, Isakova T, Jorgensen H, Komaba H, et al.
Kidney Int
. 2025 Jan;
107(3):405-423.
PMID: 39864017
In 2017, Kidney Disease: Improving Global Outcomes (KDIGO) published a Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Since...
4.
Komaba H, Imaizumi T, Hamano T, Fujii N, Abe M, Hanafusa N, et al.
Kidney Int Rep
. 2024 Oct;
9(10):2956-2969.
PMID: 39430172
Introduction: Secondary hyperparathyroidism (SHPT) affects bone metabolism and may lead to bone fragility. However, there is conflicting evidence as to whether parathyroid hormone (PTH) levels are associated with fracture risk...
5.
Suzuki K, Soeda K, Komaba H
J Bone Miner Metab
. 2024 Jul;
42(4):463-469.
PMID: 39060498
The kidneys play an important role in the regulation of phosphate and calcium balance and serum concentrations, coordinated by fibroblast growth factor 23 (FGF23), parathyroid hormone (PTH), and 1,25-dihydroxyvitamin D...
6.
7.
Miura H, Nakamura A, Kurosaki A, Kotani A, Motojima M, Tanaka K, et al.
BMC Genomics
. 2024 Jun;
25(1):568.
PMID: 38840068
Background: Transgenic (Tg) mice are widely used in biomedical research, and they are typically generated by injecting transgenic DNA cassettes into pronuclei of one-cell stage zygotes. Such animals often show...
8.
Yamamoto S, Jorgensen H, Zhao J, Karaboyas A, Komaba H, Vervloet M, et al.
Kidney Int Rep
. 2024 May;
9(4):863-876.
PMID: 38765600
Introduction: Secondary hyperparathyroidism (SHPT) increases the risk of fractures and cardiovascular (CV) disease in patients on hemodialysis (HD). The relationship between parathyroid hormone (PTH) and outcomes has been inconsistent, possibly...
9.
Nakagawa Y, Komaba H
Endocrinol Metab (Seoul)
. 2024 May;
39(3):407-415.
PMID: 38752265
Parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) each play a central role in the pathogenesis of chronic kidney disease (CKD)-mineral and bone disorder. Levels of both hormones increase...
10.
Soeda K, Komaba H, Nakagawa Y, Kawabata C, Wada T, Takahashi H, et al.
J Nephrol
. 2024 Mar;
37(5):1339-1349.
PMID: 38512372
Background: Hyponatremia is implicated in pathological bone resorption and has been identified as a risk factor for bone fracture in the general population. However, there are limited data on the...