Hiroo Kumagai
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Explore the profile of Hiroo Kumagai including associated specialties, affiliations and a list of published articles.
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Articles
83
Citations
2127
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Recent Articles
1.
Nagata W, Takayama E, Nakagawa K, Koizumi A, Ohsawa Y, Goto H, et al.
Clin Exp Rheumatol
. 2024 Mar;
42(3):658-665.
PMID: 38436267
Objectives: Several therapeutic agents have been developed and used for the clinical treatment of systemic lupus erythematosus (SLE). In cases where SLE is accompanied by severe organ failures, such as...
2.
Yamamoto K, Oda T, Uchida T, Takechi H, Oshima N, Kumagai H
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38255818
Renal biopsy is the gold standard for making the final diagnosis and for predicting the progression of renal disease, but monitoring disease status by performing biopsies repeatedly is impossible because...
3.
Goto H, Nakashima H, Mori K, Tanoue K, Ito S, Kearney B, et al.
Am J Physiol Renal Physiol
. 2023 Dec;
326(3):F338-F351.
PMID: 38095023
A major complication of heat-related illness is the development of acute kidney injury (AKI) and damage to kidney tubular cells. Because kidney tubular cells use fatty acids as a major...
4.
Oshima N, Onimaru H, Yamashiro A, Goto H, Tanoue K, Fukunaga T, et al.
Hypertens Res
. 2023 Sep;
47(1):46-54.
PMID: 37710035
Hypertension is well-known to often coexist with diabetes mellitus (DM) in humans. Treatment with sodium-glucose cotransporter 2 (SGLT2) inhibitors has been shown to decrease both the blood glucose and the...
5.
Ito S, Goto H, Tanoue K, Koiwai K, Ishikiriyama T, Kearney B, et al.
J Leukoc Biol
. 2023 Feb;
113(4):400-413.
PMID: 36802006
The mortality rate for acute kidney injury (AKI) due to sepsis remains high, and effective therapies based on its pathogenesis remain elusive. Macrophages are crucial for clearing bacteria from vital...
6.
Shirai S, Yasuda T, Kumagai H, Matsunobu H, Ichikawa D, Shibagaki Y, et al.
Clin Exp Nephrol
. 2023 Jan;
27(4):340-348.
PMID: 36705811
Background: Clinical factors affecting renal prognosis in patients with immunoglobulin A nephropathy (IgAN) and low urinary protein excretion (U-Prot) remain unclear. This study evaluated such factors in patients with clinical...
7.
Ishinoda Y, Uto A, Yamada Y, Okazaki M, Asada H, Wakamatsu S, et al.
BMC Endocr Disord
. 2022 Dec;
22(1):300.
PMID: 36461073
Background: 17α-hydroxylase deficiency (17OHD) is a rare autosomal recessive disorder. Aldosterone levels are usually low in patients with 17OHD. However, among the approximately 150 cases of 17OHD reported to date,...
8.
Goto H, Nakashima M, Nakashima H, Noguchi M, Imakiire T, Oshima N, et al.
Am J Physiol Renal Physiol
. 2022 Jul;
323(3):F243-F254.
PMID: 35796461
Heatstroke can cause acute kidney injury (AKI), which reportedly progresses to chronic kidney disease. Kidney macrophages may be involved in such injury. Although heat acclimation (HA) provides thermal resilience, its...
9.
Goto H, Shoda S, Nakashima H, Noguchi M, Imakiire T, Ohshima N, et al.
Nephrol Dial Transplant
. 2022 May;
38(3):644-654.
PMID: 35511214
Background: Since heatstroke-induced acute kidney injury (AKI) can progress to chronic kidney disease, it would be useful to detect heatstroke-induced AKI and severe heat-related illness in the early phase. We...
10.
Ito S, Nakashima M, Ishikiriyama T, Nakashima H, Yamagata A, Imakiire T, et al.
Kidney Blood Press Res
. 2022 Feb;
47(4):277-290.
PMID: 35104825
Introduction: In diabetic nephropathy (DN), mitochondrial dysfunction and leakage of mitochondrial DNA (mtDNA) are caused by the downregulation of superoxide dismutase 2 (SOD2). mtDNA induces the activation of Toll-like receptor...