Hiroko Nishimura
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Explore the profile of Hiroko Nishimura including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
107
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Recent Articles
1.
Nishimura H, Yang Y
Biochim Biophys Acta Biomembr
. 2021 Jul;
1863(10):183688.
PMID: 34242632
Water conservation is one of the most challenging processes for terrestrial vertebrates and is necessary for their survival. Birds are the only vertebrate animals other than mammals that have the...
2.
Nishimura H, Sequeira-Lopez M
Comp Biochem Physiol A Mol Integr Physiol
. 2021 Jan;
254:110879.
PMID: 33385525
The renin-angiotensin system (RAS) evolved early among vertebrates and remains functioning throughout the vertebrate phylogeny and has adapted to various environments. The RAS is crucial for the regulation of blood...
3.
Hoy J, Nishimura H, Mehalic T, Yaoita E, Gomez R, Paxton R, et al.
Gen Comp Endocrinol
. 2020 Jun;
296:113533.
PMID: 32561435
Renin or a renin-like enzyme evolved in ancestral vertebrates and is conserved along the vertebrate phylogeny. The ontogenic development of renin, however, is not well understood in nonmammalian vertebrates. We...
4.
Nishimura H
Anat Sci Int
. 2016 Oct;
92(2):215-247.
PMID: 27718210
Renin substrate, biological renin activity, and/or renin-secreting cells in kidneys evolved at an early stage of vertebrate phylogeny. Angiotensin (Ang) I and II molecules have been identified biochemically in representative...
5.
Yaoita E, Nishimura H, Nameta M, Yoshida Y, Takimoto H, Fujinaka H, et al.
J Histochem Cytochem
. 2015 Sep;
64(1):67-76.
PMID: 26416242
Nephrin, a major intercellular junction (ICJ) molecule of mammalian podocytes in the renal glomerulus, is absent in the avian genome. We hypothesized that birds use ICJ molecules other than nephrin...
6.
Nishimura H, Yang Y
Am J Physiol Regul Integr Comp Physiol
. 2013 Sep;
305(11):R1201-14.
PMID: 24068044
For terrestrial vertebrates, water economy is a prerequisite for survival, and the kidney is their major osmoregulatory organ. Birds are the only vertebrates other than mammals that can concentrate urine...
7.
Ikezumi Y, Suzuki T, Karasawa T, Yamada T, Hasegawa H, Nishimura H, et al.
Am J Nephrol
. 2013 Aug;
38(2):149-57.
PMID: 23920104
Background: Recent reports suggest that low birthweight (LBW) is a risk factor for kidney diseases, including focal segmental glomerulosclerosis (FSGS), although the underlying pathological mechanism remains unknown. Podocyte loss triggers...
8.
Ruiz-Feria C, Yang Y, Thomason D, White J, Su G, Nishimura H
Comp Biochem Physiol A Mol Integr Physiol
. 2009 Aug;
154(4):429-36.
PMID: 19689927
Before sexual maturation, chickens (Gallus gallus) show high blood pressure (BP) and neointimal plaques in the lower abdominal aortae (AbA). We investigated age/sex-related changes in pulse wave velocity (PWV), elastin,...
9.
Lau K, Yang Y, Cook G, Wyatt R, Nishimura H
Gen Comp Endocrinol
. 2009 Jan;
160(3):288-94.
PMID: 19135443
Birds and mammals are the only vertebrates that can concentrate urine. Avian kidneys contain structurally primitive loopless nephrons and also more advanced looped nephrons, in the cortical and medullary regions,...
10.
Nishimura H
Pflugers Arch
. 2008 Feb;
456(4):755-68.
PMID: 18278509
Although birds and mammals have evolved from primitive tetrapods and advanced divergently, both can conserve water by producing hyperosmotic urine. Unique aspects in the avian system include the presence of...